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24 hour protein urine test

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24-hour urine protein measures the amount of protein excreted in urine over a 24-hour period.  We shall explain you the details of the procedure below:


Reason for 24 hour protein urine test

Protein is one compound that should not be present in your urine or is present in negligible amounts. Presence of small amounts of protein in urine is medically termed as microalbuminuria.

Quantitative analysis of protein in urine would help to diagnose: 

  • Proteinuria- presence of abnormally high amounts of protein in urine
  • Kidney disease or kidney malfunction
  • Diabetes, hypertension
  • Congestive heart failure
  • Bladder cancer
  • Amyloidosis – presence of amyloid protein in urine
  • Kidney infection
  • Nephrotic syndrome
  • Glomerulonephritis
  • Hemolytic uremic syndrome
  • Pre-eclampsia- high blood pressure and protein in your urine after 20 weeks of pregnancy

However, presence of protein in urine may also be a transient condition which could occur from stress, over exercise, etc.


Before taking 24 hour protein urine test

Tell your doctor about your medical condition, the symptoms you are experiencing and the medicines you are taking and everything regarding your lifestyle. If you are planning for pregnancy or are pregnant, then make sure you disclose that to your doctor.

Your doctor will further explain you the test. Your food and drinks will be normal. Do not exercise on the day of the test.


How to take perform 24 hour protein urine test

First decide the 24 hour period of collecting the urine. You will be given a container for that. Remember to discard the first urine after waking up from morning; you can collect the sample then onwards. Make sure your private parts are clean and the urine doesn’t mix with semen or vaginal secretions.

Cap the container and keep it in a cool place, refrigerator would also be suitable. Label the container and hand it over to the concerned person in the diagnostic centre after completion of 24 hour period.

You may also be given a plastic bag or a pouch to collect the urine. You have to make your baby wear the pouch inside the diaper or his/underpants for a day to ensure that the urine gets collected properly.


What happens after the test?

Your urine is sent to the laboratory, where protein levels will be quantified. Your test reports will be handed over on the same day or the next day.


Interpretation of test reports

The standard value of 24 hours protein in urine differs from one laboratory to another. Nonetheless, for a 24-hour urine collection, the normal value is usually 0 to 0.15 gm/24 hr. If high level of protein has been detected then it could be an indication of a kidney problem or any of those aforementioned complications or it could be a temporary problem.

However, before confirming any disease, your doctor would repeat the test, order random urine test or conduct other diagnostic tests specific for the suspected disease.


How effective is 24 hour protein urine test

The test is easy and effective way to determine protein levels. If you have followed the instructions of your doctor properly then there’s no reason as to why it should show a false negative report. The only factors that might interfere with test results are dehydration, urine amalgamated with semen, blood or secretions, stress, exercise etc. So, you have to be careful.

Written by: healthplus24.com team
Date last updated: July 15, 2014

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