What should I know before taking this drug
Additional information if any
Ziprasidone is a prescription drug available from your pharmacy store only with the prescription of a qualified medical practitioner.
Common uses of ziprasidone
Ziprasidone is used in the treatment of acute psychosis, Schizophrenia, Mania agitation and aggressive behaviour.
- Take Ziprasidone exactly as prescribed by your doctor. If do not understand these instructions ask your pharmacist, nurse or doctor to explain them to you.
- Take oral dose of Ziprasidone preferably with meals to avoid gastric upset.
- Take Ziprasidone at regular intervals as advised by your doctor for it to be effective.
- Ziprasidone may take few wks to show its beneficial effects. However continue to take it as advised.
- Do not take the medication in larger amounts or for longer duration than recommended by your doctor.
- Do not skip doses or stop taking Ziprasidone without consulting your doctor as it may lead to withdrawal symptoms.
- Always remember to inform your health expert if you are currently taking any OTC or prescription drugs like,
- Anti histamine like terbenafine, Astemizole
- Antibiotics like erythromycin, Rifampicin, Sparfloxacin, Moxifloxacin
- Diuretics like furosemide
- Anti arrhythmic drugs like Dofetilide, Quinidine, sotalol
- Other anti psychotics like Pimozide, thioridazone
- Inform your doctor if you have following medical diseases , as Ziprasidone should be used cautiously in these conditions
- Family history of long QT interval
- History of heart attack and heart failure
- Bone marrow depression
- Seizure disorder
- Parkinson’s disease
- Renal and liver disease
- Electrolyte disturbance
Pregnant woman: Ziprasidone belongs to FDA pregnancy category C. This means that ziprasidone may harm an unborn baby if used during pregnancy but potential benefit may warrant use of the drug in pregnant woman despite potential risks. Always inform your doctor if you are pregnant or are planning for conception.
Lactating women: It is not known whether ziprasidone passes into breast milk or if it could harm the baby. Do not take ziprasidone with out first talking to doctor if you are breast feeding a baby.
If you are diabetic on this medication keep a close watch on your blood sugar levels.
Use as directed by your physician, your physician prescribes depending on the severity of disease.
Use the complete course of medication as prescribed by your physician even though you feel better after one or two days of usage of medication.
In case of overdose contact your nearest poison control centre or emergency medical centre for immediate care by physician.
The overdose symptoms of Ziprasidone include
- Palpitations. Irregular heartbeat
- Restlessness, irritability
- Uncontrolled movements of hands, legs, face, tongue, jaw
- Allergic reaction like swollen lips, hives, difficulty in breathing, rashes. Peeling of skin etc
- Uncontrolled movements of the hands, legs, tongue, face.
- Prolonged painful erection in men (Priapism)
- Tremors, Jerking movements or stiffness
- Fever, muscle stiffness. Sweating
- Jaundice (yellowing of skin eyes).
How do I store ziprasidone?
Store ziprasidone at room temp (15 – 30 degrees C). Avoid excessive heat, moisture or direct sunlight, never store in the bathroom.
Keep it out of reach of children. Make sure that any leftover portion is disposed off safely.
- Avoid getting dehydrated or extreme heat as Ziprasidone may increase the risk of having heat stroke. Take plenty of oral fluids in hot weather and during exercise.
- Ziprasidone causes giddiness, drowsiness and visual disturbances as side effects. Therefore when affected do not drive, operate heavy machinery or perform unsafe tasks.
- Ziprasidone may rarely cause a group of symptoms called as Neuroleptic Malignant syndrome characterised by difficulty in swallowing, Muscle stiffness, rapid heart rate, visual disturbances, etc, stop the drug immediately and consult your doctor.
- Avoid alcohol as it may increase side effects due to Ziprasidone.
- Ziprasidone should be used cautiously in elderly patients as they more prone for side effects like muscle stiffness, involuntary movements etc
- Regular monitoring of your liver function test, renal function test, and Body electrolytes is required when on this medication to look for possible side effects.
- Ziprasidone should not be used in elderly patient to treat psychotic condition related to dementia as it may cause fatal heart attack and pneumonia in these patients.
It is imp to read manufacturing packaging instruction carefully if available and always do not hesitate to consult pharmacist or physician for any information.
Written by: Healthplus24 team
Date last updated: July 03, 2012