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General Information
What should I know before taking this drug
Dosage information
Adverse reactions
Additional information if any
Relicalm tab (Reliance)
Trazine tab (Sun)

Type: OTC/Prescription/schedule

Trifluoperazine is a prescription drug available from your pharmacy store only with the prescription of a qualified medical practitioner.


Trifluoperazine pronounced as: trye floo oh PER a zeen 

What is trifluoperazine?

Trifluoperazine is an anti psychotic medication belonging to phenothiazine group of drugs. 

Common uses of trifluoperazine

Trifluoperazine is used in the short term management of anxiety and in the treatment of psychotic disorder like Schizophrenia, acute psychosis

  • Take Trifluoperazine exactly as prescribed by your doctor. If do not understand these instructions ask your pharmacist, nurse or doctor to explain them to you.
  • Take Trifluoperazine tablet with meals to avoid stomach upset at regular intervals for it to be effective.
  • Trifluoperazine may take few weeks to show its beneficial effects. Do not take the medication in larger amounts or for longer duration than recommended by your doctor as it may lead to drug- dependence.
  • Do not skip doses or stop taking Trifluoperazine without consulting your doctor.
  • Always remember to inform your health expert if you are currently taking any OTC or prescription drugs like,
    1. Diuretics like furosemide etc
    2. Anti histamine like terbenafine, Astemizole
    3. Anti convulsants like phenytoin. Phenobarbitone, carbamazepine
    4. Antibiotics like erythromycin, Rifampicin
    5. Tricyclic antidepressants
    6. Anti hypertensive’s or other heart medication
    7. Lithium (mood stabilizer)
  • Inform your doctor if you have following medical diseases , as Trifluoperazine should be used cautiously in these conditions
    1. Bone marrow depression
    2. Benign hyperplasia of prostate
    3. Seizure disorder
    4. Parkinson’s disease
    5. Closed angle glaucoma
    6. Kidney or liver disease

When not to take trifluoperazine

Do not use trifluoperazine in psychotic disorders relating to dementia. 

Pregnant woman: Trifluoperazine belongs to FDA pregnancy category C. This means that trifluoperazine may harm an unborn baby if used during pregnancy but potential benefit may warrant use of the drug in pregnant woman despite potential risks. Always inform your doctor if you are pregnant or are planning for conception.
Lactating women: It is not known whether trifluoperazine passes into breast milk or if it could harm the baby. Do not take trifluoperazine with out first talking to doctor if you are breast feeding a baby.
Trifluoperazine causes giddiness, drowsiness and visual disturbances as side effects. Therefore when affected do not drive, operate heavy machinery or perform unsafe tasks.  
Avoid drinking alcohol.
Trifluoperazine is available in the form of tablet. 

Doses for trifluoperazine

Use as directed by your physician, your physician prescribes depending on the severity of disease.

Use the complete course of medication as prescribed by your physician even though you feel better after one or two days of usage of medication. 

What about if I missed the dose of trifluoperazine

If it is almost the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not take two doses at same time to cover up the missed dose. 

What should I do if I over dosage trifluoperazine

In case of overdose contact your nearest poison control centre or emergency medical centre for immediate care by physician.

The overdose symptoms of Trifluoperazine include
  • Loss of consciousness 
  • Restlessness, agitation
  • Irregular heart rate
  • Uncontrolled movement of hand, legs, face, jaws

What are the common side effects of trifluoperazine?

Trifluoperazine may cause following side effects

  • Agitation 
  • Loss of appetite
  • Drowsiness 
  • Nasal congestion
  • Decrease in sex drive
  • Dryness of mouth
  • Giddiness when getting up from sitting or lining down position

When to consult the health expert about the side effects of trifluoperazine

Consult your doctor immediately if notice following symptoms.

  • Allergic reaction like swollen lips, hives, difficulty in breathing, rashes. Peeling of skin etc
  • Uncontrolled movements of the hands, legs, tongue, face
  • Tremors, Jerking movements or stiffness
  • Menstrual disturbances
  • Breast enlargement in men
  • Urinary retention
  • Jaundice (yellowing of skin eyes)
  • Visual disturbances

How do I store trifluoperazine?

Store trifluoperazine at room temp (15 – 30 degrees C). Avoid excessive heat, moisture or direct sunlight, never store in the bathroom.

Keep it out of reach of children. Make sure that any leftover portion is disposed off safely.
  • Avoid getting dehydrated or extreme heat as Trifluoperazine may increase the risk of having heat stroke. Take plenty of oral fluids in hot weather and during exercise
  • Trifluoperazine may rarely cause a group of symptoms called as Neuroleptic Malignant syndrome characterised by difficulty in swallowing, Muscle stiffness, rapid heart rate, visual disturbances, etc, stop the drug immediately and consult your doctor.
  • Trifluoperazine should be used cautiously in elderly patients as they more prone for side effects like muscle stiffness, involuntary movements etc.
  • Regular monitoring of your liver function test, complete cell counts, renal function test and eye examination is required when on this medication to look for possible side effects.
It is imp to read manufacturing packaging instruction carefully if available and always do not hesitate to consult pharmacist or physician for any information.



Written by: Healthplus24 team
Date: Mar30th,09

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