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General Information
 
Uses
 
What should I know before taking this drug
 
Precautions
 
Dosage information
  
Adverse reactions
 
Storage
 
Additional information if any
 

Brand names and manufacturer

Thioril tab (Torrent (Mind))

Melleril tab (Novartis C H)
 

Type: OTC/Prescription/schedule

Thioridazine is a prescription drug available from your pharmacy store only with the prescription of a qualified medical practitioner. 

Pronunciation

Thioridazine pronounced as: thye-oh-RID-a-zeen 

What is thioridazine?

Thioridazine is an antipsychotic drug belonging to Phenothiazine group of drugs. 

Common uses of thioridazine

Thioridazine is used in the treatment of Schizophrenia, psychotic depression only when other drugs have failed to work. 

  • Take thioridazine exactly as prescribed by your doctor. If do not understand these instructions ask your pharmacist, nurse or doctor to explain them to you.
  • Take thioridazine at regular intervals as advised by your doctor for it to be effective.
  • Thioridazine may take few wks to show its beneficial effects. However continue to take it as advised.
  • Do not take the medication in larger amounts or for longer duration than recommended by your doctor.
  • Do not skip doses or stop taking thioridazine without consulting your doctor as it may lead to withdrawal symptoms.
  • Always remember to inform your health expert if you are currently taking any OTC or prescription drugs like,
    1. Anti arrhythmic drugs like quinidine, propranolol
    2. Anti HIV drugs like Ritonavir, Indinavir
    3. Anti Parkinson drugs like Levadopa
    4. SSRIs like Fluoxetine, paroxetine
    5. Rifampicin (antibacterial)
    6. Antibiotics like Clarithromycin, Sparfloxacin,erythromycin
  • Inform your doctor if you have following medical diseases , as Thioridazine should be used cautiously in these conditions
    1. Pheochromocytoma (adrenal gland tumour)
    2. Angle closure glaucoma
    3. CNS depression, coma
    4. Seizure disorder
    5. Parkinson’s disease
    6. Renal and liver disease

When not to take thioridazin

Do not take thioridazine if you have history of heart attack, heart failure, arrhythmias.  

What are the precautions I should follow for thioridazine?

Children:
Old people:
Pregnant woman:
Thioridazine belongs to FDA pregnancy category C. This means that thioridazine may harm an unborn baby if used during pregnancy but potential benefit may warrant use of the drug in pregnant woman despite potential risks. Always inform your doctor if you are pregnant or are planning for conception. 

Lactating women: It is not known whether thioridazine passes into breast milk or if it could harm the baby. Do not take thioridazine with out first talking to doctor if you are breast feeding a baby.
 
Other:
 

What are the dosage forms thioridazine is available in the market

Thioridazine is available in the form of tablets. 

Doses for thioridazine

Use as directed by your physician, your physician prescribes depending on the severity of disease. 

Use the complete course of medication as prescribed by your physician even though you feel better after one or two days of usage of medication.
 

What about if I missed the dose of thioridazine

If it is almost the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not take two doses at same time to cover up the missed dose. 

What should I do if I over dosage thioridazine

In case of overdose contact your nearest poison control centre or emergency medical centre for immediate care by physician. The overdose symptoms of Thioridazine include

  • Muscle spasm
  • Shortness of breath
  • Drowsiness
  • Palpitations. Irregular heartbeat
  • Uncontrolled movements of hands, legs, face, tongue, jaw
  • Loss of consciousness

What are the common side effects of thioridazine?

Thioridazine may cause following side effects

  • Loss of appetite
  • Nausea, Vomiting 
  • Nasal stuffiness 
  • Dryness of mouth
  • Agitation

When to consult the health expert about the side effects of thioridazine

Consult your doctor immediately if notice following symptoms.

  • Allergic reaction like swollen lips, hives, difficulty in breathing, rashes. Peeling of skin etc
  • Uncontrolled movements of the hands, legs, tongue, face, jaw
  • Menstrual irregularities
     
  • Visual disturbances
  • Mask like face, unresponsiveness to surroundings
  • Jaundice (yellowing of skin eyes)
  • Tremors, Jerking movements or stiffness
  • Fever, muscle stiffness. Sweating
  • Fast irregular heartbeat.

How do I store thioridazine?

Store thioridazine at room temp (15 – 30 degrees C). Avoid excessive heat, moisture or direct sunlight, never store in the bathroom.

Keep it out of reach of children. Make sure that any leftover portion is disposed off safely.
 
  • Avoid getting dehydrated or extreme heat as Thioridazine may increase the risk of having heat stroke. Take plenty of oral fluids in hot weather and during exercise.
  • If you are diabetic on this medication keep a close watch on your blood sugar levels.
  • Thioridazine causes giddiness, drowsiness as side effects. Therefore when affected do not drive, operate heavy machinery or perform unsafe tasks.
  • Thioridazine may rarely cause a group of symptoms called as Neuroleptic Malignant syndrome characterised by difficulty in swallowing, Muscle stiffness, rapid heart rate, visual disturbances, etc, stop the drug immediately and consult your doctor.
  • Avoid alcohol as it may increase side effects due to Thioridazine.
  • Thioridazine should be used cautiously in elderly patients as they more prone for side effects like muscle stiffness, involuntary movements etc.
  • Regular monitoring of your Electrocardiogram (ECG), Body electrolytes and eye examination is required when on this medication to look for possible side effects.
It is imp to read manufacturing packaging instruction carefully if available and always do not hesitate to consult pharmacist or physician for any information.

 

Written by: Healthplus24 team
Date: Mar22nd,09