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General Information
What should I know before taking this drug
Dosage information
Adverse reactions
Additional information if any

Brand names and manufacturer

Rovamycin forte (NPIL)

Rovamycin RTU (NPIL)

Type: OTC/Prescription/schedule

Spiramycin is a prescription drug available from your pharmacy store only with the prescription of a qualified medical practitioner. 


Spiramycin pronounced as: speer-a-MYE-sin

What is spiramycin?

Spiramycinis an anti infective / antibacterial drug belonging to Macrolide group of antibiotics. 

Spiramycin is used in the treatment of following condition
  • Toxoplasmosis
  • Prevent transmission of toxoplasmosis to the unborn child
  • Protozoan infection like amoebiasis, Balantidiasis, malaria, cryptosporidiosis

How to use spiramycin

Take Spiramycin exactly as prescribed by your doctor. If you do not understand ask your pharmacist, nurse or doctor to explain them to you. 

Take oral dose of Spiramycin on empty stomach 1hr before or 2hrs after meals with 1 glass of water at regular intervals as prescribed by your doctor.
Do not skip any doses. Continue to take it even when you feel better.
You must complete the entire course of medication to get maximum benefit; else the infection will not clear completely and in due course result in development of resistance.
  • Do not take Spiramycin if you are on following medication as it can interact with these drugs and cause life threatening arrhythmias
    1. Astemizole (antihistamine)
    2. Terfenadine (antihistamine)
    3. Cisapride
    4. Pimozide
  • Spiramycin is known to interact with wide variety of drugs. Inform your doctor if you are taking any OTC or prescription medicine like
    1. Anticoagulants (warfarin)
    2. Antifungal drugs(fluconazole, itraconazole and ketoconazole)
    3. Anti migraine drugs(ergotamine)
    4. Anti convulsants (carbamazepine)
    5. Anti hypertensive like sotalol,felodipine,
  •   Inform your doctor if you have following medical conditions as Spiramycin should be used cautiously in the below mentioned conditions
    1. Liver disease
    2. History of obstruction to bile ducts
    3. Family history of Long QT interval or sudden cardiac arrest
    4. History cardiac arrhythmias
Lactating women: It is not known whether spiramycin passes into breast milk or if it could harm the baby. Do not take spiramycin with out first talking to doctor if you are breast feeding baby.
Avoid grape fruit and juices when on Spiramycin medication.

What are the dosage forms spiramycin is available in the market

Spiramycin is available as tablet, suspension, and injection. Your doctor will prescribe them depending on the severity and condition of the disease. 

Doses for spiramycin

Use as directed by your physician, your physician prescribes depending on the severity of disease. 

Use the complete course of medication as prescribed by your physician even though you feel better after one or two days of usage of medication.
For detailed dosage information, consult your doctor who will prescribe you depending on the severity of the disease.

What about if I missed the dose of spiramycin

If it is almost the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not take two doses at same time to cover up the missed dose.


What should I do if I over dosage spiramycin

In case of overdose contact your nearest poison control centre or emergency medical centre for immediate care by physician.

The overdose symptoms of Spiramycin are

  • severe diarrhoea,
  • nausea &vomiting,
  • abdominal pain and
  • Hearing impairment.

What are the common side effects of spiramycin?

Spiramycin may causes following side effects like

  • Diarrhoea 
  • Nausea and vomiting 
  • Abdominal discomfort
  • Loss of appetite
  • Rash associated with itching

When to consult the health expert about the side effects of spiramycin

Consult your doctor immediately if notice following symptoms.

  • Allergic reaction like swollen lips, hives, difficulty in breathing, rashes peeling of skin, itching, blistering etc
  • Severe diarrhoea associated with bloody stools
  • Jaundice( yellowing of eyes and skin)
  • Decrease in amount of urine passed
  • Palpitations, irregular heartbeat

How do I store spiramycin?

Store spiramycin at room temp (15 – 30 degrees C). Avoid excessive heat, moisture or direct sunlight, never store in the bathroom.

Keep it out of reach of children. Make sure that any leftover portion is disposed off safely.

What is the most important information I should know about spiramycin

Antibiotics usually cause mild diarrhoea. Consult your doctor immediately if it is severe, associated with mucus or bloody stools, as it could be sign of new infection or pseudomembranous colitis.

When used for long duration, your doctor may ask you to undergo laboratory test like complete cell count, liver function test, to look for possible side effects.

It is imp to read manufacturing packaging instruction carefully if available and always do not hesitate to consult pharmacist or physician for any information.

Written by: Healthplus24 team
Date: Mar17th,09