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Brand names with manufacturer:

Zocor and Simvador


Prescription drug

What is it: 

Simvastatin belongs to a class of drugs known as statins- which are chemically known as HMG-CoA reductase inhibitors. HMG-CoA reductase makes cholesterol and as the medicine works on this enzyme, your cholesterol levels are controlled.



Simvastatin is used to lower total cholesterol and LDL (bad) cholesterol in the body


With the decrease in cholesterol, risks of atherosclerosis, heart attack and stroke are also reduced.

What should I know before taking this drug:

You should know the dosage, side effects, drug interactions and precautions before taking the drug. Consume the tablet as exactly advised by your doctor.

How to take it: 

Simvastatin is taken orally with a glass of water before or after food, preferably during evening.

Adverse reactions/side effects

The most common side effects include muscle pain, headache, dizziness, nausea, diarrhoea, stomach pain, indigestion, forgetfulness, etc. Simvastatin is also known to affect normal functioning of liver, breakdown of muscle cells called (rhabdomyolysis), increase of serum glucose and memory loss.
Adverse reactions from Simvastatin include severe allergy and rashes over skin and around mouth accompanied by shortness of breath. Report your doctor immediately on noticing abnormality.



Your doctor will take special care before prescribing to children below 10 years old or children (both boys and girls) who haven’t reached their puberty

Old people: 

Simvastatin is used very cautiously in old people, especially if above 65 years.

Pregnant women: 

Simvastatin is not given to pregnant women or those planning for pregnancy, because cholesterol is a key component required for fetal development.

Lactating women: 

Simvastatin is not recommended to lactating mothers as the medicine is passed onto breast milk which is potentially harmful for the infant

What should I do if

I miss dose(s)

Never take extra dose. However, you can take the missed dose if you remember immediately, otherwise skip the missed dose and resume the next schedule.

I take over dose 

Call your doctor immediately

Dosage form: 

This is an extended release tablet and is available as 5, 10, 20, 40 and 80 mg tablets. The dosage form differs from one individual to another which depends on the patient’s age, medical condition, and response/adverse effects to treatment.


The treatment is usually initiated with 5, 10 to 20 mg tablet once a day in the evening with food. The dosing may be increased with severity of risk facts of having coronary artery disease and may be used in combination with other lipid lowering drugs.


Should be stored at room temperature in a cool and dry place, out of reach of children.

Additional information if any

Ask your doctor if it’s safe to drive as you would experience dizziness
Do not give your medicine to anyone
Follow the diet plan and other changes in lifestyle as recommended by your doctor
Never stop taking the pill without asking your doctor
Always consult your doctor if you have any doubts or sense any abnormality

Written by: team

Date last updated: December 26, 2014