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General Information
 
Uses
 
What should I know before taking this drug
 
Precautions
 
Dosage information
  
Adverse reactions
 
Storage
 
Additional information if any
 
Aerosporin (GSK)
Poly – B (Samarth) 
Polymyxin B is a prescription drug available from your pharmacy store only with the prescription of a qualified medical practitioner. 
Polymyxin B pronounced as: POL-ee-MIX-in B 
Polymyxin B is an anti infective / antibacterial drug. 
Polymyxin B is used in the treatment of infections of skin, ear and eye. 
Take oral dose of Polymyxin B before or after meals with 1 glass of water at regular intervals as prescribed.
 
Take plenty of oral fluids when on Polymyxin B medication.
 
Do not skip any doses. Continue to take it even when you feel better.
 
You must complete the entire course of medication to get maximum benefit; else the infection will not clear completely and in due course result in development of resistance.
 
  • Always remember to inform your health expert if you are currently taking any OTC or prescription drugs like other antibiotics like amikacin, gentamicin, Amphotericin B, NSAIDs etc
  • Inform your doctor if you have following medical conditions as Polymyxin B should be used cautiously in the below mentioned conditions
    1. Renal impairment
    2. Perforated ear drum
    3. Myasthenia gravis
  • Always inform your doctor if you are pregnant or are planning for conception.
  • Inform your surgeon or dentist if your undergoing any planned procedure when on Polymyxin B medication as it increases the side effects of the anaesthetic drugs.
Do not use polymixin B if you are allergic to it or any of its ingredients.
 
Children: Polymyxin B medication should be used cautiously in neonates and infants.
Old people: Polymyxin B medication should be used cautiously in elderly individual.
Pregnant woman: Polymixin B belongs to FDA pregnancy category B. This means that Polymixin B is safe during pregnancy and is not expected to cause any harm to the unborn baby. Always inform your doctor if you are pregnant or are planning for conception.
 
Lactating women: It is not known whether Polymixin B passes into breast milk or if it could harm the baby. Do not take Polymixin B with out first talking to doctor if you are breast feeding baby.
 
Other: 
Polymyxin B is available as injection eye drops and ear drops. Your doctor will prescribe it depending on the severity of the disease. 
Use as directed by your physician, your physician prescribes depending on the severity of disease.
 
Use the complete course of medication as prescribed by your physician even though you feel better after one or two days of usage of medication.
 
For detailed dosage information, consult your doctor who will prescribe you depending on the severity of the disease. 
If it is almost the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not take two doses at same time to cover up the missed dose. 
In case of overdose contact your nearest poison control centre or emergency medical centre for immediate care by physician. The overdose symptoms of Polymyxin B are
  • Convulsions
  • Tingling and numbness of extremities
  • Muscle spasm
  • Decrease in the amount of urine
Polymyxin B may causes following side effects like
  • Redness and pain at the site of injection
  • Drowsiness
  • Nausea & vomiting
  • Fever
Consult your doctor immediately if notice following symptoms.
  • Allergic reaction like swollen lips, hives, difficulty in breathing, rashes etc
  • Decrease in the amount of urine passed
  • Muscle weakness
  • Tingling and numbness in extremities
  • Confusion, psychosis, convulsions
  • Palpitations, irregular heartbeat
  • Visual disturbances
Store polymyxin B at room temp (15 – 30 degrees C). Avoid excessive heat, moisture or direct sunlight, never store in the bathroom.
Keep it out of reach of children. Make sure that any leftover portion is disposed off safely.
 
Polymyxin B can cause drowsiness. Do not take part in activities which require you to be alert and avoid alcohol.
 
Regular monitoring of renal function is required to look for side effects when on Polymyxin B injection.
 
Take plenty of oral fluids and strictly avoid dehydration when on Polymyxin B.
 
Inform your surgeon or dentist if your undergoing any planned procedure when on Polymyxin B medication as it increases the side effects of the anaesthetic drugs.
 
It is imp to read manufacturing packaging instruction carefully if available and always do not hesitate to consult pharmacist or physician for any information. 
 
 

Written by: Healthplus24 team
Date: Mar7th,09