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General Information
What should I know before taking this drug
Dosage information
Adverse reactions
Additional information if any
Kenadion inj [ Samarth ] 
Injek inj [ Neon Labs ] 
Phytonadione is a prescription drug available from your pharmacy store only with the prescription of a qualified medical practitioner. 
Phytonadione (pronounced as: fye toe na DYE own 
Phytonadione is a man made form of vitamin K. 
Phytonadione is used in the following

  • Treatment of Vitamin K deficinency due to malabsorption
  • To treat and prevent bleeding due to Vitamin K deficiency in newborn neonates
  • Management of bleeding due to over use of anticoagulant drugs.
  • Take phytonadione exactly as prescribed by your doctor. If do not understand these instructions ask your pharmacist, nurse or doctor to explain them to you.
  • Take oral dose of phytonadione at regular intervals with full glass of water
  • Phytonadione injection is administered as slow intravenous injection by your healthcare professional under aseptic precautions.
  • Do not take the medication in larger amounts or for longer duration than recommended by your doctor. 
  • Do not skip doses or stop taking phytonadione without consulting your doctor.
  • Always remember to inform your health expert if you are currently taking any OTC or prescription drugs like,
    1. Oral anticoagulants like warfarin, dipyridamole
    2. NSAIDs like aspirin, diclofenac, naproxen etc
    3. cholestyramine ( cholesterol lowering drug)
  • Inform your doctor if you have following medical conditions, as Phytonadione should be used cautiously in these conditions
    1. premature low birth weight babies (<2.5kg)
    2. liver disease
    3. Hemolytic anaemia
Do not use phytonadione if you are allergic to it. 
Children: Phytonadione should not be used in children.
Old people:
Pregnant woman: Phytonadione belongs to FDA pregnancy category C. This means that phytonadione may harm an unborn baby if used during pregnancy but potential benefit may warrant use of the drug in pregnant woman despite potential risks. Always inform your doctor if you are pregnant or are planning for conception.
Lactating women: It is not known whether phytonadione passes into breast milk or if it could harm the baby. Do not take phytonadione with out first talking to doctor if you are breast feeding a baby.
Phytonadione is available as injection and as tablet in combination with other drugs. Your doctor will prescribe it depending on the condition of the disease. 
Use as directed by your physician, your physician prescribes depending on the severity of disease.
Use the complete course of medication as prescribed by your physician even though you feel better after one or two days of usage of medication. 
If it is almost the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not take two doses at same time to cover up the missed dose. 
In case of overdose contact your nearest poison control centre or emergency medical centre for immediate care by physician. 
Phytonadione may cause following side effects
  • Pain, redness at the site of injection
  • Flushing 
  • Bluish lips, nails
  • Giddiness
Consult your doctor immediately if notice following symptoms.
  • Allergic reaction like swollen lips, hives, difficulty in breathing, rashes. Peeling of skin etc 
  • Sweating 
  • Shortness of breath
  • Rapid heartbeat
Store phytonadione at room temp (15 – 30 degrees C). Avoid excessive heat, moisture or direct sunlight, never store in the bathroom.
Keep it out of reach of children. Make sure that any leftover portion is disposed off safely.
  • Regular monitoring of clotting test [prothrombin time (PT with INR)] is required after starting phytonadione to monitor for possible side effects.
  • Inform your surgeon or dentist before any planned procedure regarding Phytonadione medication.
  • Consult your doctor immediately if you notice any unusual bleeding form in spite of taking medication.
It is imp to read manufacturing packaging instruction carefully if available and always do not hesitate to consult pharmacist or physician for any information. 

Written by: Healthplus24 team
Date: Mar28th,09