General Information
What should I know before taking this drug
Dosage information
Adverse reactions
Additional information if any
Brand names and manufacturer
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Penicillamine is a prescription drug available from your pharmacy store only with the prescription of a qualified medical practitioner.
Penicillamine is pronounced as:  pen ih SILL ah meen 
Penicillamine is an antirheumatic drug. (Disease modifying anti rheumatic drug (DMARD’s)) 
Penicillamine is used in the treatment of 
  • Wilson’s disease
  • Rheumatoid arthritis
  • Kidney stones
Take penicillamine on empty stomach, one hour before or two hours after the meals.
Do not stop the medication abruptly. If you stop the medication consult your doctor if you restart. You need monitoring under health care provider.
Do not use penicillamine if you are
Pregnant or breast feeding
Have blood disorder like decreased number of white blood cells
Penicillamine should not be used in children as its efficacy is not established.
Old people: 
Penicillamine is excreted by the kidneys. Caution is advised for using Penicillamine as older people have decreased kidney function. In clinical trials it is suggested that elderly people are at greater risk for skin rash.
Pregnant woman:
Penicillamine belongs to  FDA pregnancy category D. This means that penicillamine can harm an unborn baby and cause birth defects if used during pregnancy. Do not use penicillamine with out your doctor consent however its use is justified if the benefits to the mother outweigh the risks. Always inform your doctor if you are pregnant or are planning for conception.
Lactating women:
Penicillamine passes into breast milk and harm nursing baby. Do not use penicillamine with out the consent from your doctor if you are breastfeeding your child.
Penicillamine is available in the form of tablets.
Use as directed by your physician, your physician prescribes depending on the severity of disease.
Use the complete course of medication as prescribed by your physician even though you feel better after one or two days of usage of medication.
If it is almost the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not take two doses at same time to cover up the missed dose. 
In case of overdose contact your nearest poison control centre or emergency medical centre for immediate care by physician. 
Following are the side effects 
  • Stomach pain, Nauses, vomiting, diarrhea
  • Itching or rash
  • Wrinkling skin
  • Rapid breathing 
If you notice any of the following side effects notify your doctor immediately
  • Sever allergic reactions like skin rash, itching.
  • Dizziness
  • Trouble in breathing
  • Dark urine or blood in the urine
  • Yellowing of eyes/skin
Store Penicillamine at room temp (15 – 30 degrees C / 59 – 86 degrees F). Avoid excessive heat, moisture or direct sunlight, never store in the bathroom.
Keep it out of reach of children. Make sure that any left over portion is disposed off safely.  
What is the most important information I should know about penicillamine 
Do not share this medication with others.
Inform your doctor if you are allergic to penicillins.
Laboratory tests such complete blood tests and liver functions tests should be performed to monitor the side effects of penicillamine. 

It is imp to read manufacturing packaging instruction carefully if available and always do not hesitate to consult pharmacist or physician for any information.

Written by: Healthplus24 team
Date last updated: May 15, 2012

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