Generic Name:

paroxetine (pa ROX a teen)

Brand Names:

Paxil, Brisdelle, Paxil CR, Pexeva, Paroxetine


Paxil is an antidepressant drug of the selective serotonin reuptake inhibitor (SSRI) type. It tends to affect chemicals in the brain that become unbalanced.


It is a prescription only drug.


Paxil has many uses to treat mental disorders such as:

  • Depression
  • Panic attacks
  • Obsessive-compulsive disorder
  • Anxiety disorder
  • Post-traumatic disorder

Paxil also helps improve the mood, sleep, energy level as well as appetite. Thus, improving the daily quality of life. It also helps precipitate any fear in mind, anxiety, panic attacks as well as unwanted thoughts. Those with compulsive disorder will find, their urge to count, hand-wash, clean, check or anything related to compulsion is greatly reduced after taking Paxil.

Paxil is also used to treat social phobia, social anxiety disorder, premenstrual dysphoric disorder (PMDD) as well as hot flashes related to menopause.

How to Take Paxil?

Paxil should be taken as prescribed by the doctor. Do not change the dose or amount or frequency of the drug without informing the doctor. Swallow whole the extended-release tablet. Do not chew, crush or break the tablet.

The oral suspension should be measured properly before taking. Use the dose-measuring spoon or medicine cup or dosing syringe to measure the liquid.

The symptoms may take about 4 weeks to show some improvement. Thus, keep taking the medicine as advised by the doctor. Never stop taking the medicine without the advice of the doctor. It could lead to may unwanted and unpleasant withdrawal symptoms.

Side Effects

Side effects of paxil include:

  • Nausea
  • Drowsiness and dizziness
  • Sweating
  • Blurred vision
  • Yawning
  • Decrease sex drive, impotence, or problems having an orgasm

These were some of the common side effects that can affect some patients. Inform your doctor, if these side effects worsen. Other serious side effects that require a doctor’s attention include:

  • Allergic reaction to the drug leading to skin rash, hives, breathing problems, swelling of the face, lips, mouth, throat, etc.
  • Sudden changes in mood or behavior
  • Panic attacks
  • Problems sleeping
  • Hyperactivity that is either physical or mental
  • Increase in depression
  • Agitation, irritation, hostility, aggressiveness, etc.
  • Sudden development of suicidal thoughts
  • Unusual behavior or extreme talkativeness, racing thoughts
  • Changes in appetite
  • Easy bruising, unusual bleeding or coughing up blood
  • Hallucinations, fast heart rate, overactive reflexes, nausea, vomiting, fainting, loss of coordination and other symptoms indicating high levels of serotonin


Before taking the first dose of the drug, be sure to inform the doctor if you have any allergies to any ingredient in the drug. Inform the doctor about any previous medical history or family history of liver problems, kidney problems, seizures, bipolar/manic-depressive disorder, intestinal ulcers, bleeding problems, etc.

Paxil can lead to drowsiness or dizziness. Thus, do not drive or operate machinery or any activity that requires you to remain alert at all times. Geriatric use may lead to a condition called hyponatremia (salt loss) especially when diuretics are also used. In children, it may cause loss of appetite and weight. Thus, keep their weight and height in check, when using this drug.

Paxil is not to be used when pregnant. Thus, inform the doctor if you are pregnant or planning to get pregnant. The drug can harm the fetus, especially when used in the first trimester. The babies born may show feeding or breathing problems, muscle stiffness, constant crying, seizures, etc. Paxil can pass through breast milk. Thus, speak to your doctor about using the drug, before nursing a baby.

Drug Interactions

Paxil can interact with other drugs and supplements. Inform the doctor if you are taking or have recently taken thioridazine, antiplatelet drugs like clopidogrel, NSAIDs, blood thinners, etc. Using aspirin along with Paxil, increases the risk of bleeding.

Paxil may slow-down the removal of other drugs from the body as well as affect the way they function. These drugs include antiarrhythmics, tetrabenzine, tamoxifen, pimozide, phenothiazines, etc. Avoid MAO inhibitors with Paxil, as it can lead to many serious problems, including death.

Do not use drugs that increase serotonin level, leading to, serotonin syndrome or toxicity. Avoid drugs that cause drowsiness, sleepiness or anxiety. Do not drink alcohol as it also increases drowsiness.


Keep Paxil in a cool, dry and dark place. Keep away from children and pets.

Written by: team

Date last updated: June 18, 2015