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General information
What should I know before taking this drug?
Adverse reactions
Additional information if any


Paroxetine is pronounced as: pa ROX a teen

 Type: OTC / Prescription

Paroxetine is a prescription drug available from your pharmacy store only with the prescription of a qualified medical practitioner.

What is paroxetine

Paroxetine belongs to a class of drugs called selective serotonin reuptake inhibitors (SSRI). Paroxetine is an anti depressant drug.

  • Paroxetine is used to treat depression, obsessive compulsive disorder, anxiety disorder, panic attacks, post traumatic stress disorder and pre- menstrual syndrome called premenstrual dysphoric disorder. 
  • Paroxetine improves mood, sleep, appetite and energy levels in the body.
  • Paroxetine decreases anxiety, unreasonable fears, obsession and irritability.

How to use paroxetine

  • Use Paroxetine as instructed on the label or as prescribed by the doctor/pharmacist. Do not take the drug in more or less amounts.
  • If Paroxetine is taken as a tablet, swallow the entire tablet. Do not crush or chew the tablet. In case it is taken in the liquid form, make sure to shake the product properly before each use.
  •  Paroxetine can be taken with or without food.
  • Use of Paroxetine should not be stopped suddenly, as this may worsen your condition. If you want to discontinue it, start by slowly reducing your dosage. However, it is best to consult your doctor before you stop taking this medication. At times it is advised to continue with the medication even if you feel well.
  • Paroxetine takes a few weeks to take full affect. In order to improve your condition, use the drug as long as directed by the physician. 


What are the precautions I should follow for paroxetine?

Children: Safety and effectiveness is not confirmed in children. Caution is advised while usages in children as children are at risk of suicidal thoughts.

Older people: Caution is advised while usages in older people as they are have decreased renal clearance.

Pregnant women: Paroxetine belongs to FDA pregnancy category D. This means that paroxetine can harm an unborn baby and cause birth defects if used during pregnancy. Do not use paroxetine with out your doctor consent however its use is justified if the benefits to the mother outweigh the risks. Always inform your doctor if you are pregnant or are planning for conception.
Lactating women: paroxetine passes into breast milk and harm nursing baby. Do not use paroxetine with out the consent from your doctor if you are breastfeeding your child.
  • Use Paroxetine under strict medical supervision. 
  • Before starting the treatment, inform your doctor if you have any medical history related to heart disease, glaucoma, asthma, liver problems and kidney problems. Also inform him of any personal or family medical history of any other mental/mood conditions as well as the list of substances you are allergic to.
  • In case if you have diabetes, inform your physician before hand as during paroxetine treatment blood sugar levels may become uncontrolled. 
  • Before any surgery, inform your doctor/dentist that you are using paroxetine. 
  • As the paroxetine causes dizziness and lightheadedness do not handle heavy machinery and do not drive during the treatment.   

 What are the common side effects of paroxetine

Common side effects of paroxetine include: 

  • Dry mouth 
  • Blurred vision
  • Headache, Drowsiness, Dizziness
  • Constipation
  • Nausea, Vomiting
  • Loss of appetite
  • Stomach cramps
  • Weight gain/loss
  • Diarrhea


How do I store paroxetine

Store paroxetine at room temp (15 – 30 degrees C). Avoid excessive heat, moisture or direct sunlight, never store in the bathroom.
Keep it out of reach of children. Make sure that any leftover portion is disposed off safely.

  • In case paroxetine is consumed by a pregnant woman, her child may be born with inherent heart/lung problems. Please consult your doctor before using the medication during pregnancy.
  • Paroxetine is used for treating depression. However, in younger adults below 24 years of age, the drug may cause severe side effects like mental / mood changes, suicidal tendency and increased depression. Therefore, Paroxetine is not recommended for people who are below 24 years of age.
  • Avoid using paroxetine if you have suffered from any heart problem in the recent past and if you have taken MAO inhibitor in the last 14 days.
  • Consult your doctor immediately if you experience any severe side effect like sleep disorders, anxiety, unusual behavioral changes and panic attacks.
  • Consult your doctor frequently during the first few weeks of treatment in order to check the changes in your behavior during the treatment.

Written by: Healthplus24 team
Date last updated: June 24, 2012

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