Ornidazole

Generic Name

Ornidazole

Trade Name(s)

Ofodol, Avrazor, Biter, Levocn OZ, Gatrid- OZ, Ornida (100 ml), Tibéral, Richet, Xynor

Therapeutic Classification of ornidazole

Amebicides

Indications

Ornidazole is an antiamoebic agent that is given to patients with amoebic dysentery.

Sponsored links

Contraindications

People who are hypersensitive to Ornidazole or other nitroimidazole drugs should avoid it. It comes under Pregnancy Category C. Thus, one should exert caution when pregnant. Lactating women should also refrain from use of Ornidazole.

The drug may cause dizziness, headaches and tremors. Thus, one should avoid driving or operating machinery. Patients with renal and hepatic impairment should also exert caution when using the drug. Precautions have to be taken for patients of CNS diseases such as epilepsy or multiple sclerosis.

Uses of ornidazole

Ornidazole is an anti-bacterial, anti-infection and anti-protozoal drug. It is prescribed to treat different health conditions due to anaerobic infections, bacterial vaginosis, amoebic liver abscess, amoebic dysentery, hepatic amoebias, giardiasis, trichomoniasis and Crohn’s disease.

Dosage and When To Take

The drug is available in the form of tablets. These tablets are to be taken by mouth. It can also be given intravenously in the form of an infusion, if required. Dosage for adults 0.5 g to 1.5 g for 5 to 10 days, once a day, according to the type of parasitic infection.

In case of children, 25 mg/kg to 40 mg/kg as a single dose for 5 to 10 days, depending on the type of infection.

Hemodialysis patients can be given a supplemental dose of about 50% of the usual dose before they undergo dialysis. Patients with hepatic disorders may require a double interval period between doses.

Sponsored links

The tablets need to be taken after meals with plenty of water. Never chew, break, or dissolve the tablet. Always swallow it as a whole piece.Complete the entire course of tablet, as advised by the physician, even if you feel better or the symptoms disappear. If you do not complete the dose, it may lead to a relapse.

Side Effects of ornidazole

The side effects of the Ornidazole are usually mild and common. However, if the symptoms persist or worsen or start bothering you, speak to your physician immediately.

  • Headache
  • Nausea
  • Drowsiness
  • Dizziness
  • Vomiting
  • Insomnia
  • Unusual tastes
  • Skin reactions like rash, itching and inflammation
  • Temporary loss of consciousness

Serious side effects of Ornidazole that require immediate medical attention include:

  • Confusion
  • Severe dizziness
  • Severe diarrhea
  • Numbness
  • Tremors
  • Seizures
  • Jaundice
  • Tingling sensation
  • Bloody stools
  • Rigidity
  • Lack of coordination

Other Drug Interactions

Avoid taking Ornidazole with other anticoagulants as it has potential to interact negatively. It can also interact with muscle relaxants, thus, these drugs should be administered together with due caution. This drug can cause adverse effect on the animal fetus, studies have shown. Thus, the drug may lead to adverse effects on the human fetus. Therefore, one has to be careful when prescribing it to a pregnant patient.

Storage of ornidazole

The drug can be stored at room temperature in a cool and dry place. Keep the drug away from the reach of children.

This was some information related to Ornidazole. This information will serve as a guide related to the indications, dosage, how and when to take or not take and side effects of the drug. However, make sure you follow the advice of your physician and do not self-medicate. These facts are only for your information and do not take place of expert medical advice.

Written by: healthplus24.com team

Date last updated: May 05, 2015