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General Information
What should I know before taking this drug
Dosage information
Adverse reactions
Additional information if any
Depin (Zy.medica)
Nicardia (JB Chemicals) 
Nifedipine is a prescription drug available from your pharmacy store only with the prescription of a qualified medical practitioner. 
Nifedipine pronounced as: nye-FED-ih-peen 
Nifedipine an antihypertensive / Calcium Channel Blocker 
Nifedipine is used in the treatment of hypertension, angina (chest pain), hypertrophic cardiomyopathy and Raynaud’s disease.
  • Take Nifedipine exactly as prescribed by your doctor. If do not understand these instructions ask your pharmacist, nurse or doctor to explain them to you.
  • Do not take the medication in larger amounts or for longer duration than recommended by your doctor. Take this medication with a full glass of water.
  • Take Nifedipine at the same time every day to avoid forgetting. 
  • Do not skip doses or stop taking Nifedipine without consulting your doctor. Stopping suddenly may worsen hypertension or cause other serious cardiac problems like worsening of angina.
  • Always remember to inform your health expert if you are currently taking any OTC or prescription drugs like,
    1. Cimetidine( anti histamine)
    2. Antibiotics like erythromycin, Rifampicin
    3. Anti convulsants like carbamazepine, phenytoin
    4. Anti hypertensive drugs like beta blocker
    5. Anti fungal like itraconazole, Fluconazole
  • Inform your doctor if you have following medical diseases , as Nifedipine should be used cautiously in these conditions
    1. Liver disease
    2. Kidney disease
    3. History of heart failure or heart attack within 1mnth
    4. Diseases of blood vessel like aortic stenosis, coronary artery disease,
Do not use nifedipine if you are suffering from heart disease.

Old people: Caution is advised for using in older people.

Pregnant woman: Nifedipine belongs to FDA pregnancy category C. This means that nifedipine may harm an unborn baby if used during pregnancy but potential benefit may warrant use of the drug in pregnant woman despite potential risks. Always inform your doctor if you are pregnant or are planning for conception.

Lactating women: It is not known whether nifedipine passes into breast milk or if it could harm the baby. Do not take nifedipine with out first talking to doctor if you are breast feeding a baby.
Avoid taking grape fruit or juices when on Nifedipine.
Nifedipine causes gum swelling. Maintain good oral hygiene by regularly brushing & flossing your teeth. 
Nifedipine is available in the form of tablets and capsules. 
Use as directed by your physician, your physician prescribes depending on the severity of disease.
Use the complete course of medication as prescribed by your physician even though you feel better after one or two days of usage of medication. 
If it is almost the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not take two doses at same time to cover up the missed dose. 
In case of overdose contact your nearest poison control centre or emergency medical centre for immediate care by physician.
The overdose symptoms of Nifedipine are
  1. Shortness of breath
  2. Chest pain
  3. Light headedness, fainting
  4. Fast or slow irregular heartbeat.
Nifedipine may cause following side effects
  • Headache 
  • Constipation
  • Nausea 
  • Giddiness 
  • Oedema of the feet
  • Sleep disturbances
  • Swelling of gums
  • Increased urination
Consult your doctor immediately if notice following symptoms.
  • Allergic reaction like swollen lips, hives, difficulty in breathing, rashes. Peeling of skin etc
  • Oedema in both the feet
  • Chest pain, breathing difficulty,
  • Palpitations, Irregular heart beat
  • Jaundice (yellowing of eyes, skin)
  • Unusually fast or slow pulse
Store nifedipine at room temp (15 – 30 degrees C). Avoid excessive heat, moisture or direct sunlight, never store in the bathroom.
Keep it out of reach of children. Make sure that any leftover portion is disposed off safely.
  • Never stop Nifedipine abruptly without consulting your doctor as it causes rebound hypertension and worsening of angina or attack of MI.
  • It causes dizziness when used for the first time when getting up from sitting or lying down position due to postural hypotension. Therefore when dizzy do not drive or get involve in activity which requires you to be alert
  • Visit your doctor regularly for monitoring your blood pressure and pulse rate when taking Nifedipine.
  • Hypertension often has no symptoms, so you may not even feel that you have high blood pressure. Continue using this medicine as directed, even if you feel well. You may need to use blood pressure medication for the rest of your life.
  • Adopt healthy lifestyle changes like regular exercise, healthy diet, quit smoking, alcohol to lower your blood pressure and improve your overall health. 

It is imp to read manufacturing packaging instruction carefully if available and always do not hesitate to consult pharmacist or physician for any information.


Written by: Healthplus24 team
Date: Mar22nd,09

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