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General Information
What should I know before taking this drug
Dosage information
Adverse reactions
Additional information if any
Mefliam (Cipla)
Falcital (Cadila HC) 
Mefloquine is a prescription drug available from your pharmacy store only with the prescription of a qualified medical practitioner. 
Mefloquine is pronounced as:MEFF-low-kwin 
Mefloquine is anti-infective / an anti malarial drug. 
Mefloquine is used for both the treatment and prevention of malaria .
  • Take Mefloquine exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.
  • Do not skip any doses. Continue to take it even when you feel better. You must complete the entire course of medication. If you don't, the infection will not clear completely and in due course may cause resistance to develop against the drug.
  • Take each dose with or immediately after meal with a full glass (250 ml) of water to avoid gastric upset.
  • When mefloquine is used for prophylaxis it is important to start the medication 1-2 weeks before travelling to the malaria affected areas and continue it till 4 week after leaving the malaria endemic areas.
  • In spite of taking the medication regularly you can still contract the disease. If you get fever consult your physician immediately.
  • For children who can not swallow whole tablet, the mefloquin tablet can be given by crushing and mixing with the food or water or milk this also helps to mask the bitter taste.  
  • Always remember to inform your health expert if you are currently taking any prescription drugs like beta blockers, anti arrhythmic drugs, anti depressants other antimalarials etc  
  • Inform your doctor if you have following medical conditions as mefloquine is contraindicated in the below mentioned conditions
    1. Liver diseases
    2. any psychiatric illnesses like anxiety, depression, delusions etc
    3. seizure disorder
You should not take mefloquine if you are hypersensitive to quinine and related compounds.  
Old people:
Pregnant woman: Mefloquine belongs to FDA pregnancy category C. This means that mefloquine may harm an unborn baby if used during pregnancy but potential benefit may warrant use of the drug in pregnant woman despite potential risks. Always inform your doctor if you are pregnant or are planning for conception.
Lactating women: It is not known whether mefloquine passes into breast milk or if it could harm the baby. Do not take mefloquine with out first talking to doctor if you are breast feeding a baby.
Other: Mefloquine may cause dizziness, if you feel dizzy do not drive or take part in activity in which you need to be alert
When mefloquine is used for prolonged period it is important to get periodic eye examination and liver functions test done to look for side effects 
Mefloquine is available in the form tablets. 
Use mefloquin as directed by your physician, your physician prescribes depending on the severity of disease.

For prophylaxis of malaria: 250mg once a week. Mefloquin should start taking 1-3 weeks before you travel to malaria area and in the travel and 4 weeks after leaving the malaria area.

Use the complete course of medication as prescribed by your physician even though you feel better after one or two days of usage of medication. 
If it is almost the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not take two doses at same time to cover up the missed dose. 
In case of overdose contact your nearest poison control centre or emergency medical centre for immediate care by physician.

The over dosage symptoms are similar to side effects but are more pronounced. 
The most common side effects that you may experience on taking mefloquine medication are
  • Abdominal pain
  • Diarrhoea
  • Dizziness
  • Nausea and vomiting
  • Palpitations
  • Psychiatrics symptoms like depression, anxiety
Consult you doctor immediately if you experience the following adverse effects
  • Allergic reaction like swollen lips, shortness of breath, constricting sensation in the throat etc
  • Onset of seizures
  • Severe palpitations , irregular heart beat
Store mefloquine at room temp (15 – 30 degrees C). Avoid excessive heat, moisture or direct sunlight, never store in the bathroom.
Keep it out of reach of children. Make sure that any left over portion is disposed off safely.
  • Live vaccine should not be taken when on this medication as the efficacy of the vaccine is reduced. However if you plan, take the vaccine 3 days prior to starting mefloquine medication.
  • Mefloquine is not 100%protective in prevention of malaria. Its is advised to use other mosquito protective measures like using repellents, bed nets , long sleeved clothing etc. In case you get fever, consult your doctor immediately and seek treatment for malaria.

It is imp to read manufacturing packaging instruction carefully if available and always do not hesitate to consult pharmacist or physician for any information.

Written by: Healthplus24 team
Date last updated: May 31, 2012