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General Information
 
Uses
 
What should I know before taking this drug
 
Precautions
 
Dosage information
  
Adverse reactions
 
Storage
 
Additional information if any
 

Anzolid infusion (Claris)
Linid tab (Zy Cadila)

Linezolid is a prescription drug available from your pharmacy store only with the prescription of a qualified medical practitioner.

Linezolid  pronounced as: lin EZ oh lid

Linezolid is an anti infective / antibacterial drug.

Linezolid is used in the treatment of skin &soft tissue infections, community acquired pneumonia and other respiratory tract infections

 

  • Take Linezolid exactly as prescribed by your doctor. If you do not understand ask your pharmacist, nurse or doctor to explain them to you.
  • Take oral dose of Linezolid before or after meals with 1 glass of water at regular intervals as prescribed by your doctor.
  • Linezolid is given intra muscularly or intravenously under strict aseptic precautions as prescribed by your doctor.
  • Do not skip any doses. Continue to take it even when you feel better.
  • You must complete the entire course of medication to get maximum benefit; else the infection will not clear completely and in due course result in development of resistance. 
  • Do not use SSRI antidepressants(fluoxetine, citalopram) without consulting your doctor when on Linezolid medication as it can cause high fever, sweating, anxiety, memory problems, muscle spasm etc
  • Inform your doctor if you are using any OTC or any prescription drugs like
    1. Immune suppressive drugs( cyclosporine, tacrolimus)
    2. Cold/ cough medicine containing pseudoephedrine, phenylephrine
    3. MAO inhibitors(selegiline)
    4. Anti Parkinson drugs( levadopa, carbidopa)
    5. Narcotic pain killers(fentanyl, meperidine)
  •   Inform your doctor if you have following medical conditions as Linezolid should be used cautiously in the below mentioned conditions
    1. hypertension
    2. Untreated Hyperthyroidism
    3. Adrenal gland disorder(pheochromocytoma,)
    4. Seizure disorder
    5. Any history of psychiatric illness( bipolar disorder, schizophrenia)
    6. History of low blood counts/ myelosupression.
    7. Kidney or liver disease

Do not use linezolid if you are hypersensitive to it.

Children: Extreme caution is advised for usage of linezolid in children.

Old people:
Pregnant woman: Linezolid belongs to FDA pregnancy category C. This means that linezolid may harm an unborn baby if used during pregnancy but potential benefit may warrant use of the drug in pregnant woman despite potential risks. Always inform your doctor if you are pregnant or are planning for conception.
 
Lactating women: It is not known whether linezolid passes into breast milk or if it could harm the baby. Do not take linezolid with out first talking to doctor if you are breast feeding a baby.
 
Other:
 

Linezolid is available in the form of tablets and injection.

Use as directed by your physician, your physician prescribes depending on the severity of disease. Use the complete course of medication as prescribed by your physician even though you feel better after one or two days of usage of medication.

For detailed dosage information, consult your doctor who will prescribe you depending on the severity of the disease.
 

If it is almost the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not take two doses at same time to cover up the missed dose.

In case of overdose contact your nearest poison control centre or emergency medical centre for immediate care by physician. The overdose symptoms of linezolid are extreme fatigue, fainting loss of coordination.

Linezolid may causes following side effects like

  • Abnormal taste
  • Sleep disturbances
  • Diarrhea 
  • Drowsiness 
  • Constipation 
  • Skin rash, itching

Consult your doctor immediately if notice following symptoms.

  • Allergic reaction like swollen lips, hives, difficulty in breathing, rashes peeling of skin, blistering etc
  • Severe diarrhea associated with bloody stools
  • Jaundice( yellowing of eyes and skin)
  • Fatigue, paleness of skin
  • Easy bruising and bleeding
  • Muscle pain, fast & irregular breathing
  • Palpitations
  • Blurring of vision

Store linezolid at room temp (15 – 30 degrees C). Avoid excessive heat, moisture or direct sunlight, never store in the bathroom.
Keep it out of reach of children. Make sure that any leftover portion is disposed off safely.

  • Antibiotics usually cause mild diarrhea. Consult your doctor immediately if it is severe, associated with mucus or bloody stools, as it could be sign of new infection or pseudomembranous colitis.
  • Linezolid can cause drowsiness. Avoid activities which require you to be alert.
  • Your doctor may advise you to undergo weekly test for blood cell count to look for possible side effects.
  • Avoid consumption of tyramine containing foods like cheese, soya sauce, red wine, pickled or fermented meat, tap beer etc as it can raise your blood pressure to abnormally high levels.

It is imp to read manufacturing packaging instruction carefully if available and always do not hesitate to consult pharmacist or physician for any information.

Written by: Healthplus24 team
Date last updated: May 31, 2012