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General Information
What should I know before taking this drug
Dosage information
Adverse reactions
Additional information if any

Glevo tab (Glen mark (Majesta))
Levoflox tab (Cipla (Protec))

Levofloxacin is a prescription drug available from your pharmacy store only with the prescription of a qualified medical practitioner.

Levofloxacin  pronounced as: LEE-voe-FLOX-a-sin

Levofloxacin is an anti infective / broad spectrum antibacterial drug belonging to fluoroquinolone group of antibiotics.

Levofloxacin is used in the treatment of acute sinusitis, hospital and community acquired pneumonia, urinary tract infection(UTI), respiratory infections and for treatment &post exposure prophylaxis of anthrax

  • Take levofloxacin exactly as prescribed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.
  • Take oral dose of levofloxacin before or after meals with one glass of water at regular intervals as prescribed by your doctor. Take lots of oral fluids when on this medication.
  • Do not take antacids with levofloxacin medication as it decreases the efficacy of levofloxacin. However you may take it 2 hrs before or 6hrs after taking levofloxacin medication.
  • If you are taking oral solution, take it preferably on empty stomach as prescribed by your doctor.
  • Do not skip any doses. Continue to take it even when you feel better.
  • You must complete the entire course of medication to get maximum benefit; else the infection will not clear completely and in due course result in development of resistance.
  • Levofloxacin is known to interact with wide variety of drugs. Always remember to inform your health expert if you are currently taking any OTC or prescription drugs like
    1. Anti arrhythmic drugs (Quindine, Amiodarone)
    2. Anti psychiatric drugs(thioridazine, ziprasidone, duloxetine
    3. Oral steroid drugs( betamethasone, Dexmethsaone, Prednisone )
    4. Oral hypoglycaemic drugs(glyburide)
    5. NSAIDS( Ibuprofen, Diclofenac, Indomethacin)
    6. Other antibiotics( Erythromycin)
  • Inform your doctor if you have following medical conditions as levofloxacin should be used cautiously in the below mentioned conditions
    1. Kidney disease
    2. History of tendon or joint injury
    3. Seizure disorder
    4. Diabetes
    5. Liver disease
    6. Family history of long QT interval

Levofloxacin should not be given to patients who have heart problems.

What are the precautions I should follow for levofloxacin?

Children: Caution is advised for children less than 18 years old.

Old people: Levofloxacin medication should be used cautiously in elderly individual as the risk of tendon injury is more when on this medication.

Pregnant woman: Levofloxacin belongs to FDA pregnancy category C. This means that levofloxacin may harm an unborn baby if used during pregnancy but potential benefit may warrant use of the drug in pregnant woman despite potential risks. Always inform your doctor if you are pregnant or are planning for conception.

Lactating women: It is not known whether levofloxacin passes into breast milk or if it could harm the baby. Do not take levofloxacin with out first talking to doctor if you are breast feeding a baby.

Other: Levofloxacin impairs thought process and causes drowsiness. Avoid activities which require you to be alert.

Levofloxacin is available as tablet, oral solution, injection and eye drops. Your doctor will prescribe them depending on the severity of the disease.


Use as directed by your physician, your physician prescribes depending on the severity of disease. Use the complete course of medication as prescribed by your physician even though you feel better after one or two days of usage of medication.

For detailed dosage information, consult your doctor who will prescribe you depending on the severity of the disease.

If it is almost the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not take two doses at same time to cover up the missed dose.

In case of overdose contact your nearest poison control centre or emergency medical centre for immediate care by physician.

The overdose symptoms of levofloxacin are
  • Convulsions 
  • Increased Fatigue 
  • Difficulty in breathing
  • Increased sweating
  • Tremors

Levofloxacin may causes following side effects like

  • Nausea and vomiting
  • Mood changes( irritability, confusion, anxiety)
  • Sleep disturbance( insomnia, nightmares)
  • Increased sensitivity to light
  • Drowsiness 
  • Visual disturbances 
  • Sinus inflammation(sinusitis)

Consult your doctor immediately if notice following symptoms. 

  • Allergic reaction like swollen lips, hives, difficulty in breathing, rashes. Peeling of skin etc
  • Sudden onset of pain, swelling , stiffness in joints( ankle or arm)
  • Palpitations, irregular heart beat
  • Convulsions
  • Severe diarrhoea
  • Severe depression, suicidal thoughts and mood changes
  • Jaundice (yellowing of skin and eyes)

Store levofloxacin at room temp (15 – 30 degrees C). Avoid excessive heat, moisture or direct sunlight, never store in the bathroom.
Keep it out of reach of children. Make sure that any leftover portion is disposed off safely.

  • Avoid prolonged sun exposure as Levofloxacin sensitizes the exposed skin causing burning sensation, rash etc. Use long sleeved clothes, sunscreen lotion (SPF-15) when you go out in sun to avoid photo toxicity.
  • Antibiotics may cause diarrhoea. Consult your doctor immediately if it is very severe as it could be a sign of new infection.
  • Your doctor may advise you to undergo certain lab test like complete cell count, liver function test, renal function test periodically when levofloxacin is prescribed for long duration.
  • If you are diabetic taking this medication keep a close watch on your sugar levels. 

It is imp to read manufacturing packaging instruction carefully if available and always do not hesitate to consult pharmacist or physician for any information.

Written by: Healthplus24 team
Date last updated: May 31, 2012

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