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General Information
What should I know before taking this drug
Dosage information
Adverse reactions
Additional information if any

Lervasc (Lupin)
Lerka (NPIL)

Lercanidipine is a prescription drug available from your pharmacy store only with the prescription of a qualified medical practitioner.

Lercanidipine is an anti hypertensive drug belong to calcium channel blocker.

Lercanidipine is used in the treatment of hypertension.

  • Take lercanidipine exactly as prescribed by your doctor. If do not understand these instructions ask your pharmacist, nurse or doctor to explain them to you.
  • Do not take the medication in larger amounts or for longer duration than recommended by your doctor. Take this medication with a full glass of water.
  • Take lercanidipine preferably on empty stomach half an hr before or 2 hrs after meals at the same time every day to avoid forgetting.
  • Do not skip doses or stop taking lercanidipine without consulting your doctor. Stopping suddenly may worsen hypertension or cause other serious cardiac problems like worsening of angina.
  • Avoid taking grapes or grape juice when on lercanidipine.
  • Always remember to inform your health expert if you are currently taking any OTC or prescription drugs like,
    1. Cimetidine( anti histamine)
    2. Antibiotics like erythromycin, Rifampicin
    3. Anti convulsants like carbamazepine, phenytoin
    4. Other Anti hypertensive drugs metoprolol
    5. Anti fungal like itraconazole, Fluconazole
    6. Antiviral like ritonavir
    7. Astemizole, cyclosporine etc
  • Inform your doctor if you have following medical diseases , as lercanidipine should be used cautiously in these conditions
    1. Liver disease
    2. History of heart failure or heart attack within 1mnth
    3. Diseases of blood vessel like aortic stenosis, coronary artery disease,

Do not use lercanidipine in you are suffering from liver or kidney disease and within one month of heart attack.

Old people:
Pregnant woman: Lercanidipine belongs to FDA pregnancy category C. This means that lercanidipine may harm an unborn baby if used during pregnancy but potential benefit may warrant use of the drug in pregnant woman despite potential risks. Always inform your doctor if you are pregnant or are planning for conception. 

Lactating women: It is not known whether lercanidipine passes into breast milk or if it could harm the baby. Do not take lercanidipine with out first talking to doctor if you are breast feeding a baby.
Other: Avoid taking grape fruit or juices when on lercanidipine.

Lercanidipine is available in the form of tablet.

Use as directed by your physician, your physician prescribes depending on the severity of disease. Use the complete course of medication as prescribed by your physician even though you feel better after one or two days of usage of medication.

If it is almost the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not take two doses at same time to cover up the missed dose.

In case of overdose contact your nearest poison control centre or emergency medical centre for immediate care by physician. The overdose symptoms of Lercanidipine are

  • Shortness of breath
  • Chest pain 
  • Fast or slow irregular heartbeat.

Lercanidipine may cause following side effects

  • Headache 
  • Nausea 
  • Oedema of the feet
  • Sleep disturbances
  • Swelling of gums
  • Increased urination
  • Fatigue

Consult your doctor immediately if notice following symptoms.

  • Allergic reaction like swollen lips, hives, difficulty in breathing, rashes. Peeling of skin etc
  • Oedema in both the feet
  • Chest pain, breathing difficulty,
  • Palpitations, Irregular heart beat
  • Jaundice (yellowing of eyes, skin)
  • Unusually fast or slow pulse

Store lercanidipine at room temp (15 – 30 degrees C). Avoid excessive heat, moisture or direct sunlight, never store in the bathroom.
Keep it out of reach of children. Make sure that any leftover portion is disposed off safely.

  • Do stop lercanidipine abruptly without consulting your doctor as it causes rebound hypertension and worsening of angina or attack of MI.
  • Lercanidipine causes gum swelling. Maintain good oral hygiene by regularly brushing & flossing your teeth.
  • lercanidipine causes dizziness when used for the first time when getting up from sitting or lying down position due to postural hypotension. Therefore when dizzy do not drive or get involve in activity which requires you to be alert.
  • Visit your doctor regularly for monitoring your blood pressure and pulse rate when taking lercanidipine.
  • Hypertension often has no symptoms, so you may not even feel that you have high blood pressure. Continue using this medicine as directed, even if you feel well. You may need to use blood pressure medication for the rest of your life.
  • Adopt healthy lifestyle changes like regular exercise, healthy diet, quit smoking, alcohol to lower your blood pressure and improve your overall health.

It is imp to read manufacturing packaging instruction carefully if available and always do not hesitate to consult pharmacist or physician for any information.

Written by: Healthplus24 team
Date last updated: May 31, 2012

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