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General Information
Brand names and manufacturer
Type: OTC/Prescription/schedule

What should I know before taking this drug
Dosage information
Adverse reactions
Additional information if any

Indap sr tab (Orchid (Cardiovascular))
Perifer tab (Micro Cardicare)

Indapamide is a prescription drug available from your pharmacy store only with the prescription of a qualified medical practitioner.

Indapamide is pronounced as: in-DAP-ah-mide

Indapamide is a thiazide diuretic which helps in removing excess fluid from the body. Hence, it’s also known as “water-pill”.

Indapamide is used in treatment of

  • Hypertension and 
  • Excessive fluid retention due to congestive heart failure
  • Take indapamide exactly as prescribed by your doctor. If do not understand these instructions ask your pharmacist, nurse or doctor to explain them to you.
  • Do not take the medication in larger amounts or for longer duration than recommended by your doctor. Take this medication with a full glass of water.
  • Take indapamide preferably during daytime to avoid waking up during night for urination.
  • Take plenty of oral fluids when on indapamide and avoid dehydration.
  • Do not skip doses or stop taking indapamide without consulting your doctor. Stopping suddenly may worsen hypertension.


  • Inform your doctor if you are allergic to sulpha drugs like sulphamethoxazole, etc as it may cause allergic reaction in these patients also.
  • Always remember to inform your health expert if you are currently taking any OTC or prescription drugs like,
    1. Aminoglycoside antibiotics like Gentamicin, erythromycin
    2. Antifundals like Amphotericin
    3. NSAIDs(Non steroidal anti inflammatory drugs) like aspirin, Indomethacin Ibuprofen, Diclofenac etc
    4. Corticosteroids like prednisone
    5. Lithium (mood stabilizer)
    6. Digoxin
    7. Other Anti hypertensive drugs
  • Inform your doctor if you have following medical diseases , as Indapamide should be used cautiously in these conditions
    1. Lupus erythematosus
    2. Liver disease
    3. Kidney disease
    4. Anuria( passing no urine at all)
    5. Electrolyte disturbance
    6. Gout

Do not take indapamide in sever renal and hepatic impairment.

Old people:-
Pregnant woman: Indapamide belongs to FDA pregnancy category B. This means that indapamide is safe during pregnancy and is not expected to cause any harm to the unborn baby. Always inform your doctor if you are pregnant or are planning for conception.

Lactating women: It is not known whether indapamide passes into breast milk or if it could harm the baby. Do not take indapamide with out first talking to doctor if you are breast feeding baby.

Indapamide is available in the form of tablet.

Use as directed by your physician, your physician prescribes depending on the severity of disease. Use the complete course of medication as prescribed by your physician even though you feel better after one or two days of usage of medication.

If it is almost the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not take two doses at same time to cover up the missed dose.

In case of overdose contact your nearest poison control centre or emergency medical centre for immediate care by physician.

Indapamide may cause following side effects

  • Drowsiness 
  • Loss of appetite
  • Nausea , vomiting
  • Diarrhoea 
  • Fatigue 
  • Increased sensitivity to light
  • Giddiness on standing or sitting position

Indapamide may cause following side effects

  • Drowsiness
  • Loss of appetite
  • Nausea , vomiting
  • Diarrhoea
  • Fatigue
  • Increased sensitivity to light
  • Giddiness on standing or sitting position

Store indapamide at room temp (15 – 30 degrees C). Avoid excessive heat, moisture or direct sunlight, never store in the bathroom.
Keep it out of reach of children. Make sure that any leftover portion is disposed off safely.

  • Indapamide causes dizziness on getting up from lying down or sitting position due to postural hypotension. Therefore use precaution when changing your posture.
  • Your doctor may prescribe potassium supplement along with indapamide medication as it depletes potassium from the body. Do not increase or decrease the dose without your doctor’s advice
  • Regular monitoring of body electrolyte, renal function and complete cell counts is required when on indapamide to look for side effects.
  • Indapamide sensitizes the skin to sunlight. Avoid prolong exposure to sunlight or wear long sleeved clothing& use sunscreen when you go out in sun.
  • If you are diabetic on indapamide, keep a close watch on your blood glucose levels.
  • Visit your doctor regularly for monitoring your blood pressure and pulse rate when taking indapamide.
  • Hypertension often has no symptoms, so you may not even feel that you have high blood pressure. Continue using this medicine as directed, even if you feel well. You may need to use blood pressure medication for the rest of your life.
  • Adopt healthy lifestyle changes like regular exercise, healthy diet, quit smoking, alcohol to lower your blood pressure and improve your overall health.  

It is imp to read manufacturing packaging instruction carefully if available and always do not hesitate to consult pharmacist or physician for any information.

Written by: Healthplus24 team
Date last updated: May 31, 2012