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General Information
Brand names and manufacturer
Type: OTC/Prescription/schedule

What should I know before taking this drug
Dosage information
Adverse reactions
Additional information if any
Glimepiride is a prescription drug available from your pharmacy store only with the prescription of a qualified medical practitioner. 
Glimepiride is pronounced as: glye-MEP-ir-ide 
Glimepiride is oral anti diabetic medication belongs to sulfonylurea group of drugs. 
Glimepiride is used to treat type 2 diabetes (Non insulin dependent diabetes)  
Take glimepiride exactly as prescribed by your doctor. If you do not understand these instructions ask your pharmacist, nurse or doctor to explain them to you.
Do not take the medication in larger amounts or for longer duration than recommended by your doctor.
Do not stop taking this medication unless advised by your doctor. 
Take the glimepiride with food with breakfast or main meal. 
Always remember to inform your doctor or pharmacist if you are currently taking any OTC drugs or prescription drugs like bosentan, beta blockers like atenolol, warfarin, ketoconazole, NSAIDs 

This may not be the complete list of drugs interact with glimepiride, ask your pharmacist if any other drugs interact with this medication.

Inform your doctor or pharmacist if you have any of the following medical conditions as glimepiride should be cautiously used.

  • Liver disease
  • Kidney disease
  • Heart problems
Do not take glimepiride
  • If you are allergic to it.
  • If you are suffering with diabetic ketoacidosis.
  • If you have type 1 diabetes

Old people: Glimepiride is eliminated by the kidneys. For older people due to reduced renal function glimepiride should be cautiously used. Does adjustment may be required depending on their renal function.

Pregnant woman: Glimepiride belongs to FDA pregnancy category C. This means that glimepiride may harm an unborn baby if used during pregnancy but potential benefit may warrant use of the drug in pregnant woman despite potential risks. Always inform your doctor if you are pregnant or are planning for conception.
Lactating women: It is not known whether glimepiride passes into breast milk or if it could harm the baby. Do not take glimepiride with out first talking to doctor if you are breast feeding a baby.
Avoid alcohol while using the glimepiride. Alcohol decreases blood sugar level and increases the risk hypoglycemia. 
Glimepiride is available in the form of tablet. 
Use glimepiride as directed by your physician, your physician prescribes depending on the severity of disease.
Use the complete course of medication as prescribed by your physician even though you feel better after one or two days of usage of medication. 
If it is almost the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not take two doses of glimepiride at the same time to cover up the missed dose. 
In case of overdose of glimepiride contact your nearest poison control centre or emergency medical centre for immediate care by physician.
The overdosge symptoms of glimepiride include
  • Hypoglycemic symptoms like low body temperature, dizziness, headache, confusion, blurred vision
  • Severe hypoglycemic effects likeconvulsions, coma
The following are the side effects observed for glimepiride
  • Nausea, vomiting
  • Blurred vision
  • dizziness
If you experience any of the following side affects stop the glimepiride medication and consult your doctor immediately
  • Allergic reactions like difficulty breathing, chest congestion, swelling of face, lips
  • Sever hypoglycemic effects like blurred vision, dizziness, and coma   
Store glimepiride at room temp (15 – 30 degrees C). Avoid excessive heat, moisture or direct sunlight, never store in the bathroom.
Keep it out of reach of children. Make sure that any leftover portion is disposed off safely.
  • Proper diet and regular exercise are important to keep control normal blood sugar levels.
  • It is advised to have the blood or urine glucose test to monitor the drug therapy.
  • Symptoms of low blood sugar levels are
    1. Nausea, extreme hunger, rapid heartbeat
    2. Dizziness, drowsiness, headache, restlessness, anxiety, blurred vision
    3. Convulsions, loss of consciousness, coma and low body temp.
  • Symptoms of high blood sugar levels are
    1. Excessive thirst, increased urination, increased hunger,
    2. Headache, confusion, blurred vision, weight loss, fatigue
    3. Viginal and skin infection, slow healing of sores, ulcers and cuts, Erectile dysfunction  
It is imp to read manufacturing packaging instruction carefully if available and always do not hesitate to consult pharmacist or physician for any information.

Written by: Healthplus24 team
Date last updated: May 31, 2012