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General Information
What should I know before taking this drug
Dosage information
Adverse reactions
Additional information if any

DEPZAC cap® [Cipla]
FAXTIN cap® [Ind-Swift]

Fluoxetine is a prescription drug available from your pharmacy store only with the prescription of a qualified medical practitioner.

Fluoxetine is pronounced as: floo-OX-e-teen

Fluoxetine is an Anti depressant belonging to a group of drugs called as Selective Serotonin Re-uptake Inhibitors (SSRIs)

Fluoxetine is used in the treatment of following conditions

  • Depression, 
  • Panic disorder 
  • Bulimia nervosa
  • Pre menstrual dysmorphic disorder (PMDD)
  • Obsessive Compulsive Disorder (OCD)
  • Take Fluoxetine exactly as prescribed by your doctor. If do not understand these instructions ask your pharmacist, nurse or doctor to explain them to you.
  • Take Fluoxetine at regular intervals as advised by your doctor for it to be effective.
  • Fluoxetine may take up to 3-4 wks to show its beneficial effects. However continue to take it as advised.
  • Do not take the medication in larger amounts or for longer duration than recommended by your doctor.
  • Do not skip doses or stop taking Fluoxetine without consulting your doctor as it may worsen your symptoms.
  • Always remember to inform your health expert if you are currently taking any OTC or prescription drugs like,
    1. Oral anticoagulant like warfarin
    2. Lithium (mood stabilizer)
    3. Digoxin (heart failure medicine)
    4. Diazepam
    5. Anti histamine like Terfenadine , Astemizole, cimetidine 
    6. Anti arrhythmic like Propafenone, Flecainide
    7. Other anti depressants like Amitriptyline, imipramine
  • Inform your doctor if you have following medical diseases , as Fluoxetine should be used cautiously in these conditions
    1. History of suicide attempt or thoughts
    2. Seizure disorder
    3. Liver or kidney disease
    4. On Electro convulsive therapy (ECT)
    5. Glaucoma
    6. Diabetes

Do not use Fluoxetine if you have taken Mono amine Oxidase inhibitors (MAO) like Phenelzine, Selegiline, rasagiline, Linezolid etc as it may cause life threatening reaction. Wait for at least 14 days after stopping MAO inhibitors to start taking the new medication.

Old people: Fluoxetine should be used cautiously in older people as they more prone for side effects like muscle stiffness, involuntary movements etc

Pregnant woman: Fluoxetine belongs to FDA pregnancy category C. This means that fluoxetine may harm an unborn baby if used during pregnancy but potential benefit may warrant use of the drug in pregnant woman despite potential risks. Always inform your doctor if you are pregnant or are planning for conception.
Lactating women: It is not known whether fluoxetine passes into breast milk or if it could harm the baby. Do not take fluoxetine with out first talking to doctor if you are breast feeding a baby.
Other: Avoid alcohol and other sedative drugs as it may increase side effects due to Fluoxetine.

Fluoxetine is available in the form of tablets, capsules, suspension.

Use as directed by your physician, your physician prescribes depending on the severity of disease. 
Use the complete course of medication as prescribed by your physician even though you feel better after one or two days of usage of medication.

If it is almost the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not take two doses at same time to cover up the missed dose.

In case of overdose contact your nearest poison control centre or emergency medical centre for immediate care by physician.

The overdose symptoms of Fluoxetine include
  • Delirium, confusion
  • Loss of consciousness 
  • Difficulty in breathing
  • Convulsions
  • Fast/ slow irregular heart rate
  • Severe giddiness
  • Coma

Fluoxetine may cause following side effects

  • Drowsiness 
  • Dryness of mouth
  • Decrease in sexual drive or performance
  • Difficulty in sleeping (insomnia)
  • Fatigue 
  • Diarrhoea
  • Nausea 
  • Loss of appetite

Consult your doctor immediately if notice following symptoms.

  • Allergic reaction like swollen lips, hives, difficulty in breathing, rashes. Peeling of skin etc
  • Uncontrolled movements of the hands, legs, tongue, face
  • Tremors, Jerking movements or stiffness
  • Suicidal thoughts or attempts
  • Exaggerated sense of well being
  • Fever, sweating, Muscle stiffness
  • Worsening of agitation, aggressiveness, depression
  • Hallucination, delirium
  • Prolong painful erection
  • Severe mental or mood changes
  • Visual disturbance

Store fluoxetine at room temp (15 – 30 degrees C). Avoid excessive heat, moisture or direct sunlight, never store in the bathroom.
Keep it out of reach of children. Make sure that any leftover portion is disposed off safely.

  • Fluoxetine increases the risk for suicidal thoughts or actions, worsening of depression, mood and behavioural changes especially in teenagers, young adults < 25 yrs. Care givers and family members should watch the patients closely and consult the doctor immediately if they notice any such symptoms.
  • If you are a diabetic on fluoxetine medication, keep a close watch on your blood sugar levels.
  • Fluoxetine may cause dizziness when getting up from sitting or lying down position due to postural hypotension. Use precaution while changing posture to avoid falling down.
  • Fluoxetine may rarely cause a group of symptoms called as Serotonin syndrome especially when used concurrently with MAO inhibitors which is characterised by nausea, vomiting, diarrhoea, sweating, tremors, fever, rapid irregular heart rate, agitation, confusion, hallucination etc, stop the drug immediately and consult your doctor.
  • Fluoxetine causes giddiness, drowsiness and visual disturbances as side effects. Therefore when affected do not drive, operate heavy machinery or perform unsafe tasks.
  • Fluoxetine can cause prolonged painful erection even when not having sex. When affected Consult your doctor immediately as it may lead to permanent sexual disability

It is imp to read manufacturing packaging instruction carefully if available and always do not hesitate to consult pharmacist or physician for any information.

Written by: Healthplus24 team
Date last updated: May 31, 2012 

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