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General Information
Brand names and manufacturer
Type: OTC/Prescription/schedule

What should I know before taking this drug
Dosage information
Adverse reactions
Additional information if any

Dinex EC (Cipla)
Virosine DR cap (Ranbaxy (crosslands))

Didanosine is an antiviral drug available at your pharmacy store only with the prescription of the registered medical practitioner.

Didanosine is pronounced as: dye DAN oh seen

Didanosine is an anti infective / anti viral drug.

Didanosine is used in the treatment of HIV (Human immune deficiency virus) which causes AIDS.

  • Take Didanosine medication exactly as directed by your doctor. If do not understand these instructions ask your pharmacist, nurse or doctor to explain them to you.
  • Didanosine should be taken on empty stomach at least half an hour before or 2hrs after meal with one full glass of water.
  • Do not skip any doses. Continue to take it even when you feel better. You must complete the entire course of medication. If you don't, the infection will not clear completely and may cause relapse.
  • Always remember to inform your health expert if you are currently taking any other drugs like
    1. stavudine(retroviral drug),
    2. antigout drugs(allopurinol,ribavirin)
    3. other drugs causing peripheral neuropathy
    4. Antibiotics( ciprofloxacin, tetracycline ) or OTC
  • Inform your doctor if you have following medical conditions as Didanosine should be used cautiously in the below mentioned conditions
    1. Peripheral neuropathy( tingling and numbness in extremities)
    2. History of pancreatitis
    3. Renal diseases
    4. Liver diseases
    5. Alcoholism

Do not take didanosine if you are hypersensitive to it.


Old people:
Pregnant woman: Didanosine belongs to FDA pregnancy category B. This means that didanosine is safe during pregnancy and is not expected to cause any harm to the unborn baby. Always inform your doctor if you are pregnant or are planning for conception.

Lactating women: It is not known whether didanosine passes into breast milk or if it could harm the baby. Do not take didanosine with out first talking to doctor if you are breast feeding baby.
Other: Avoid alcohol when on didanosine medication.

Didanosine is available in the form of tablet.

Use as directed by your physician, your physician prescribes depending on the severity of disease.Use the complete course of medication as prescribed by your physician even though you feel better after one or two days of usage of medication.

For detailed dosage information consult your doctor who will prescribe you depending on the severity of the disease,& body weight.

If it is almost the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not take two doses at same time to cover up the missed dose.

In case of overdose contact your nearest poison control centre or emergency medical centre for immediate care by physician.

You may experience following overdose symptoms
  • Increase fatigue
  • Jaundice( yellowing of skin or eyes)
  • Tingling and numbness in both the hands& feet 
  • Severe abdominal pain associated with nausea and vomiting
  • Visual disturbances

Didanosine may cause following side effects like

  • Diarrhoea
  • Fever
  • Rashes
  • Headache
  • Tingling and numbness
  • Unusual muscle pain and weakness

Consult your doctor immediately if notice following symptoms

  • Unusual muscle pain and weakness
  • Drowsiness
  • Irregular heart beat
  • Fast breathing
  • Tingling and numbness
  • Abdominal pain radiating to back
  • Visual disturbances

Store at room temp (15 – 30 degrees C). Avoid excessive heat, moisture or direct sunlight, never store in the bathroom.
Keep it out of reach of children. Make sure that any left over portion is disposed off safely.

  • Didanosine does not prevent transmission of HIV infection. Always avoid sexual contact with the affected individual or use effective barrier contraceptive like latex-condom.
  • HIV virus can transmit infection to the newborn baby via breast milk. Hence breast feeding should not be done.
  • HIV can pass to the unborn baby if the mother is not treated adequately during pregnancy. Therefore consult your doctor regularly and take medication as prescribed to prevent transmission.
  • Always visit your doctor regularly for thorough check up to monitor your condition and look for possible side effects of medication.
  • Your doctor may advise you to undergo periodic eye check up and laboratory test like renal function test, liver function test etc to look for possible side effects.

It is imp to read manufacturing packaging instruction carefully if available and always do not hesitate to consult pharmacist or physician for any information.

Written by: Healthplus24 team
Date last updated: November 16, 2011