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General Information
What should I know before taking this drug
Dosage information
Adverse reactions
Additional information if any
Azenam vial (Aristo)
Trezam inj (Glenmark (Majesta)
Aztreonam is a prescription drug available from your pharmacy store only with the prescription of a qualified medical practitioner.
Aztreonam is pronounced as: AZ tree oh nam
Aztreonam is an antibacterial drug belonging to Monobactum group of antibiotics.
Aztreonam is used in the treatment of severe life threatening infection like
  • Septicaemia
  • infection of urinary tract
  • Respiratory tract infections
  • pelvic infections, meningitis
  • skin and soft tissue infections
Take aztreonam exactly as prescribed by your doctor. If you do not understand ask your pharmacist, nurse or doctor to explain them to you.
Aztreonam is available as injection. It is supplied as a frozen solution.
Read the instruction leaflet provided clearly before thawing the solution.
Discard the solution if it is not clear or contains particles after thawing.
Aztreonam is given intramuscularly or intravenously under strict aseptic precaution as prescribed by your doctor.
Do not skip any doses. Continue to take it even when you feel better.
You must complete the entire course of medication to get maximum benefit; else the infection will not clear completely and in due course result in development of resistance.
  • Inform your doctor if you are currently taking prescription drugs like amikacin, netilmicin, gentamicin, streptomycin etc.
  • Inform your doctor if you are allergic to other penicillin drugs (e.g. amoxicillin, carbenicillin) and Cephalosporin drugs (cephelexin, cephaloridin) as it may cause allergic reaction in these patients.
  • Inform your doctor if you have following medical conditions as aztreonam should be used cautiously in the below mentioned conditions
    1. Liver disease
    2. Renal disease
    3. History allergy (hay fever, asthma)
If you are hypersensitive to aztreonam do not use it.

What are the precautions I should follow for aztreonam?


Old people:
Pregnant woman: Aztreonam belongs to FDA pregnancy category B. This means that aztreonam is safe during pregnancy and is not expected to cause any harm to the unborn baby. Always inform your doctor if you are pregnant or are planning for conception.
Lactating women: It is not known whether aztreonam passes into breast milk or if it could harm the baby. Do not take aztreonam with out first talking to doctor if you are breast feeding baby.
Aztreonam can decrease the efficacy of combination type birth pills. Consult your doctor for other effective contraceptives like condom, diaphragm etc to avoid pregnancy.
Aztreonam is available in the form of injection.
Use as directed by your physician, your physician prescribes depending on the severity of disease.
Use the complete course of medication as prescribed by your physician even though you feel better after one or two days of usage of medication.
For detailed dosage information, consult your doctor who will prescribe you depending on the severity of the disease.
If it is almost the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not take two doses at same time to cover up the missed dose.
In case of overdose contact your nearest poison control centre or emergency medical centre for immediate care by physician.
The overdose symptoms of aztreonam are not known.
Aztreonam may causes following side effects like
  • Tingling and numbness in extremities
  • Pain and swelling at the site of injection
  • Skin rash and itching
  • Giddiness
  • Vaginal discharge and itching
Consult your doctor immediately if notice following symptoms.
  • Allergic reaction like swollen lips, hives, difficulty in breathing, rashes peeling of skin, blistering etc
  • Severe diarrhoea
  • Fever, sore throat
  • Fatigue , pale skin
  • Jaundice (yellowing of skin eyes, clay colour stools)
  • Convulsions
  • Easy bruising & bleeding
Store aztreonam at room temp (15 – 30 degrees C). Avoid excessive heat, moisture or direct sunlight, never store in the bathroom.
Keep it out of reach of children. Make sure that any leftover portion is disposed off safely.
  • Antibiotics usually cause mild diarrhoea. Consult your doctor immediately if it is severe, associated with mucus or bloody stools, as it could be sign of new infection or pseudomembranous colitis.
  • Your doctor may advise you for regular lab test like complete cell count to look for possible side effects.
It is imp to read manufacturing packaging instruction carefully if available and always do not hesitate to consult pharmacist or physician for any information.

Written by: Healthplus24 team
Date: Feb26th,09

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