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Propranolol
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General Information
Brand names and manufacturer
Type: OTC/Prescription/schedule
Pronunciation 

Uses
 
What should I know before taking this drug
 
Precautions
 
Dosage information
  
Adverse reactions
 
Storage
 
Additional information if any
 
Ciplar (Cipla)
Betabloc (USV)
 
Propranolol is a prescription drug available from your pharmacy store only with the prescription of a qualified medical practitioner.
 
Propranolol pronounced as: proe-PRAN-oh-lol
 
Propranolol is an anti hypertensive / non selective beta blocker.
 
Propranolol is used in the treatment of following conditions
  1. Hypertension
  2. Angina( chest pain)
  3. Myocardial infarction
  4. Cardiac arrhythmias
  5. Migraine
  6. Pheochromocytoma( adrenal gland tumour)
  7. Essential tremors
  8. Preoperatively and in the management of hyper thyroid state.
  9. Portal hypertension
  • Take Propranolol exactly as prescribed by your doctor. If do not understand these instructions ask your pharmacist, nurse or doctor to explain them to you.
  • Do not take the medication in larger amounts or for longer duration than recommended by your doctor. Take Propranolol with a full glass of water.
  • Take Propranolol at the same time every day to avoid forgetting.
  • Do not skip doses or stop taking Propranolol without consulting your doctor.
  • Propranolol should be tapered gradually over a period of weeks Stopping suddenly may worsen hypertension or cause other serious cardiac problems like worsening of angina.
  • Always remember to inform your health expert if you are currently taking any OTC or prescription drugs like,
    1. Cimetidine( anti histamine)
    2. Other Anti hypertensive drugs
    3. Theophylline (asthma drug)
    4. Anti migraine drugs like ergotamine
    5. Oral anti coagulant like warfarin
  • Inform your doctor if you have following medical diseases , as Propranolol should be used cautiously in these conditions
    1. Bronchial asthma, chronic bronchitis
    2. Raynauds disease
    3. History of heart failure or heart attack within 1mnth
    4. Slow pulse rate with heart block
    5. Liver or kidney disease
    6. Diabetes
Do not use propranolol if you have 2nd and 3rd degree heart block.
 
Children:
Old people:
Pregnant woman:
1st trimester of pregnancy
Propranolol belongs to FDA pregnancy category C. This means that propranolol may harm an unborn baby if used during pregnancy but potential benefit may warrant use of the drug in pregnant woman despite potential risks. Always inform your doctor if you are pregnant or are planning for conception.
 
2nd and 3rd trimester of pregnancy
Propranolol belongs to  FDA pregnancy category D. This means that propranolol can harm an unborn baby and cause birth defects if used during pregnancy. Do not use propranolol with out your doctor consent however its use is justified if the benefits to the mother outweigh the risks. Always inform your doctor if you are pregnant or are planning for conception.
 
Lactating women: It is not known whether propranolol passes into breast milk or if it could harm the baby. Do not take propranolol with out first talking to doctor if you are breast feeding a baby.
 
Other:
Strictly avoid alcohol when on propranolol medication as it increases its side effects
 
Propranolol is available in the form of tablets, capsules and injection.
 
Use as directed by your physician, your physician prescribes depending on the severity of disease.
 
Use the complete course of medication as prescribed by your physician even though you feel better after one or two days of usage of medication.
 
If it is almost the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not take two doses at same time to cover up the missed dose.
 
In case of overdose contact your nearest poison control centre or emergency medical centre for immediate care by physician.
 
The overdose symptoms of Propranolol are
  1. Shortness of breath
  2. Wheezing
  3. Oedema of feet and ankles
  4. Slow heart rate
Propranolol may cause following side effects
  • Nausea & vomiting
  • Giddiness
  • Sleep disturbances
  • Abdominal cramps
  • Fatigue
Consult your doctor immediately if notice following symptoms.
  • Allergic reaction like swollen lips, hives, difficulty in breathing, rashes. Peeling of skin etc
  • Oedema in both the feet, unusual weight gain
  • Chest pain, breathing difficulty,
  • Palpitations, Irregular heart beat
  • Tingling & numbness in extremities
  • Behavioural changes
  • Visual disturbances
  • Cold clammy toes and fingers
Store propranolol at room temp (15 – 30 degrees C). Avoid excessive heat, moisture or direct sunlight, never store in the bathroom.
Keep it out of reach of children. Make sure that any leftover portion is disposed off safely.
 
  • Never stop Propranolol abruptly without consulting your doctor as it causes rebound hypertension and worsening of angina or attack of MI.
  • If you are a diabetic on Propranolol medication keep a close watch on your blood sugar levels as it may cause hypoglycaemia and mask its symptoms.
  • Inform your surgeon or dentist prior to any planned procedure regarding Propranolol medication as it may increase the side effects of anaesthetic drugs.
  • Inform your lab personnel regarding Propranolol medication as it may interfere with certain lab tests like glaucoma screening test, dobutamine stress echocardiography.
  • It causes dizziness when used for the first time when getting up from sitting or lying down position due to postural hypotension. Therefore when dizzy do not drive or get involve in activity which requires you to be alert.
  • Visit your doctor regularly for monitoring your blood pressure and pulse rate when taking Propranolol.
  • Hypertension often has no symptoms, so you may not even feel that you have high blood pressure. Continue using this medicine as directed, even if you feel well. You may need to use blood pressure medication for the rest of your life.
  • Adopt healthy lifestyle changes like regular exercise, healthy diet, quit smoking, alcohol to lower your blood pressure and improve your overall health.
It is imp to read manufacturing packaging instruction carefully if available and always do not hesitate to consult pharmacist or physician for any information.
 
 
Written by: Healthplus24 team
Date last updated: May 07, 2012
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Disclaimer : Every effort has been made to ensure that the information provided by healthplus24 team is accurate, up to date and complete but no guarantee is made to that effect. The information contained herein is intended to supplement not substitute for the expertise and knowledge of health care professional. The information is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, adverse effects etc. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Healthplus24 team disclaims any liability for the decisions you make based on this information.

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  Pregnancy Categories  
 
Category A
Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).

Category B
Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.

Category C
Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Category D
There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Category X
Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.
 

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