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GOUT

Introduction to Gout

Gout is a type of arthritis that is associated with inflammation and is 
caused due to crystallization of the uric acid normally present in the 
body. It affects about 1% of the general population and involves 
one or more joints in the body. Gout is more common in men aged 
above 40 years. The joints of the toes are most commonly affected 
while the heels, ankles, knees, fingers, wrists and elbows may be 
affected to a lesser extent.1, 2


Causes of gout

Causes of gout

The cause of gout has been attributed to increased levels of a 
chemical substance known as uric acid in the body. The uric 
acid is a by-product of certain metabolic reactions taking place 
in the body and is normally excreted through  the kidneys.


Risk Factors for Gout

Following are some of the risk factors that are associated with gout.4 

  • Lack of exercise
  • Obesity
  • Consumption of food such as read meat and sea food that are rich in purine (uric acid is a breakdown product of purine)
  • Increased consumption of alcohol and
  • Consumption of diuretic medication


Signs and Symptoms of Gout

Signs and symptoms of gout

Gout may either appear without any provocation (referred to as acute gout or acute gouty arthritis) or may be characterized by frequent attacks of the condition over a period of time. 

 

Diagnosis of Gout

Diagnosis of gout

The diagnosis is based on the signs and symptoms, history of underlying disorders or the presence of risk factors and certain laboratory investigations.   


Treatment of Gout

Treatment of gout

The aim of the treatment for gout is to reduce the severity of the symptoms during the acute attacks and prevent the progression into chronic states.   


Alternative Therapies of Gout

Following have an adjunctive role both in faster remission of gout and prevention of complications.2, 6

  • Weight reduction programs
  • Moderate exercises
  • Decreased consumption of purine-rich foods
  • Reduction or discontinuation of alcohol consumption, and
  • Control of hypertension and diabetes


Complications
 of Gout

Complications of gout include

  • Severe pain
  • Deformation of the joints
  • Joint destruction
  • Carpal tunnel syndrome
  • Deposition of uric acid crystals in the various soft-tissues of the body including the kidneys and heart.

 
Prevention of Gout

 

A healthy lifestyle, which includes proper diet with adequate exercise 
and decreased consumption of alcohol can avoid triggering the condition 
and also prevent further complications.

 

Following proper instructions from the doctor before consuming 
medications, especially those medications, which are required 
to be taken for a long period of time is also helpful.


Living with Gout

Although the acute form of gout may progress to the chronic type, 
early and proper treatment helps the affected individuals to lead 
a normal life with minimal complications.


Written by: Healthplus24 team
Date last updated: April 13, 2012

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References 
  1. Eggebeen AT. Gout: An update. Am Fam Physician. 2007; 76(6): 801–808, 811–812.
  2. Pittman JR, Bross MH. Diagnosis and management of gout. Am Fam Physician. 1999; 59(7).
  3. Choi HK, Mount DB, Reginato AM. Pathogenesis of gout. Ann Intern Med. 2005; 143: 499–516.
  4. Choi HK, Atkinson K, Karlson EW, Curhan G. Obesity, weight change, hypertension, diuretic use, and risk of gout in men: The health professionals follow-up study. Arch Intern Med. 2005; 165: 742––748.
  5. Schlesinger N, Diagnosis of gout: Clinical, laboratory, and radiologic findings. Am J Manag Care. 2005; 11: S443–S450.
  6. Cannella AC, Mikuls TR. Understanding treatments for gout. Am J Manag Care. 2005; 11: S451–S458.
 
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