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Gout
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GOUT

Introduction to Gout

Gout is a type of arthritis that is associated with inflammation and is caused due to crystallization of the uric acid normally present in the body. It affects about 1% of the general population and involves one or more joints in the body. Gout is more common in men aged above 40 years. The joints of the toes are most commonly affected while the heels, ankles, knees, fingers, wrists and elbows may be affected to a lesser extent.1, 2

Causes of Gout

Causes of gout

The cause of gout has been attributed to increased levels of a chemical substance known as uric acid in the body. The uric acid is a by-product of certain metabolic reactions taking place in the body and is normally excreted through  


Risk Factors for Gout
Lack of exercise, obesity, consumption of food such as read meat and sea food that are rich in purine (uric acid is a breakdown product of purine), increased consumption of alcohol and consumption of diuretic medication are some of the risk factors that are associated with gout.4 

Signs and Symptoms of Gout

Signs and symptoms of gout

Gout may either appear without any provocation (referred to as acute gout or acute gouty arthritis) or may be characterized by frequent attacks of the condition over a period of time 

Diagnosis of Gout

Diagnosis of gout

The diagnosis is based on the signs and symptoms, history of underlying disorders or the presence of risk factors and certain laboratory investigations. A complete examination of the blood, which includes estimation of the various   


Treatment of Gout

Treatment of gout

The aim of the treatment for gout is to reduce the severity of the symptoms during the acute attacks and prevent the progression into chronic states. The pain and swelling may be reduced with the use of nonsteroidal    


Alternative Therapies of Gout

Weight reduction programs, moderate exercises, decreased consumption of purine-rich foods, reduction or discontinuation of alcohol consumption, and control of hypertension and diabetes have an adjunctive role both in faster remission of gout and prevention of complications.2, 6

Complications of Gout

Complications of gout include severe pain, deformation of the joints, joint destruction, carpal tunnel syndrome, deposition of uric acid crystals in the various soft-tissues of the body including the kidneys and heart.

 
Prevention of Gout

A healthy lifestyle, which includes proper diet with adequate exercise and decreased consumption of alcohol can avoid triggering the condition and also prevent further complications. Following proper instructions from the doctor before consuming medications, especially those medications, which are required to be taken for a long period of time is also helpful.


Living with Gout

Although the acute form of gout may progress to the chronic type, early and proper treatment helps the affected individuals to lead a normal life with minimal complications.


Written by: Healthplus24 team
Date last updated: July 13, 2011

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References 

 

  1. Eggebeen AT. Gout: An update. Am Fam Physician. 2007; 76(6): 801–808, 811–812.
  2. Pittman JR, Bross MH. Diagnosis and management of gout. Am Fam Physician. 1999; 59(7).
  3. Choi HK, Mount DB, Reginato AM. Pathogenesis of gout. Ann Intern Med. 2005; 143: 499–516.
  4. Choi HK, Atkinson K, Karlson EW, Curhan G. Obesity, weight change, hypertension, diuretic use, and risk of gout in men: The health professionals follow-up study. Arch Intern Med. 2005; 165: 742––748.
  5. Schlesinger N, Diagnosis of gout: Clinical, laboratory, and radiologic findings. Am J Manag Care. 2005; 11: S443–S450.
  6. Cannella AC, Mikuls TR. Understanding treatments for gout. Am J Manag Care. 2005; 11: S451–S458.
 
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