Causes of Miscarriage

Following are the most important known causes of spontaneous abortion.

• Genetic and uterine abnormalities

• Endocrine and immune system dysfunctions 

• Infectious agents 

• Environmental pollutants 

• Psychogenetic factors and 

• Endometriosis

Some of the risk factors that have been associated with increased incidences of spontaneous pregnancy loss include

• Advanced maternal age

• Maternal alcohol abuse

• Maternal cigarette smoking

• Medications

• Multiple previous elective abortions

• Previous spontaneous abortion and

• Chronic exposure to toxins.

Certain maternal disorders such as poorly controlled diabetes, celiac disease and autoimmune diseases also play a role.^1,2