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HIV and TB

An immunocompromised host is a very good candidate for TB infection and development of the active disease. HIV weakens the immune system and thus allows for the development of TB.

Someone who is HIV-positive and infected with TB bacilli is many times more likely to become sick with TB than someone infected with TB bacilli who is HIV-negative.

HIV and TB form a lethal combination, each speeding the other’s progress. Tuberculosisis a leading cause of death among people who are HIV-positive. In Africa, HIV is the single most important factor contributing to the increase in incidence of TB since 1990.1,2

WHO and its international partners have formed the TB/HIV Working Group,3 which develops global policy on the control of HIV-related TB and advises on how those fighting against TB and HIV can work together to tackle this lethal combination.

The interim policy on collaborative TB/HIV activities describes steps to create mechanisms of collaboration between TB and HIV/AIDS programs, to reduce the burden of TB among people and reducing the burden of HIV among TB patients.

 

Next page: Multi drug resistant to tuberculosis

Written by: Healthplus24 team
Date last updated: July 12, 2011

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References 
  1. WHO declares TB an emergency in Africa. Available at: http://www.who.int/tb. Accessed on: March 28, 2008.
  2. Chaisson RE, Martinson NA. Tuberculosis in Africa - Combating an HIV-Driven Crisis, N Engl J Med 2008; 358(11):1089–1092.
  3. TB/HIV working Group. Available at: http://www.stoptb.org/wg/tb_hiv/. Accessed on: 24 March, 2008.
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