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Diagnosis of cold sores
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Presentation and Diagnosis of cold sores

The first symptoms usually appear within 1 or 2 weeks after contact with an infected person. The lesions usually last for 7–10 days, then begin to resolve. Initial symptoms of itching, burning or tingling sensation may occur about 2 days before lesions appear. The infection is associated with mild fever.

In a classic case of herpes labialis, six stages of the sore are recognized:
  • Prodrome—localized tingling, itching or burning around the lips, mouth and gums.

  • Erythema formation.

  • Appearance of small blisters filled with clear yellowish fluid. 

  • Ulceration of blisters.

  • Blisters break, ooze and form crusts.

  • Crusts slough to reveal pink, healing skin

The diagnosis is made on the basis of the appearance or culture of the lesion. Examination may also show enlarged lymph nodes in the neck or groin.

Written by: healthplus24 team
Date last modified: August 10, 2011

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